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m (→Microscopic) |
m (→Microscopy: w) |
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*Well-circumscribed. | *Well-circumscribed. | ||
=== | ===Microscopic=== | ||
Features - classic type:<ref>{{Ref PBoD|1016-7}}</ref><ref name=Ref_GUP293>{{Ref GUP|293}}</ref>, 3 P's [[mnemonic]]: | |||
*Pale cytoplasm, with wisps of eosinophilic material; the cells are not completely clear, they have "cobwebs". | *Pale cytoplasm, with wisps of eosinophilic material; the cells are not completely clear, they have "cobwebs". | ||
*Perinuclear clearing, i.e. a pale halo surrounds the nucleus - '''key feature'''. | *Perinuclear clearing, i.e. a pale halo surrounds the nucleus - '''key feature'''. | ||
*Periphery of cell distinct, i.e. cell membrane is easy to discern. | *Periphery of cell distinct, i.e. cell membrane is easy to discern. | ||
Features - eosinophilic variant:<ref name=Ref_GUP293>{{Ref GUP|293}}</ref> | |||
*Eosinophilic (finely granular) cytoplasm. | *Eosinophilic (finely granular) cytoplasm. | ||
*Perinuclear clearing - '''key feature'''. | *Perinuclear clearing - '''key feature'''. | ||
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Notes: | Notes: | ||
*May have psammoma bodies. | *May have [[psammoma bodies]]. | ||
Image: [http://commons.wikimedia.org/wiki/File:Oncocytic_chromophobe_rcc_high_mag.jpg Oncocytic chromophobe RCC ( | Image: [http://commons.wikimedia.org/wiki/File:Oncocytic_chromophobe_rcc_high_mag.jpg Oncocytic chromophobe RCC (WC)]. | ||
===IHC=== | ===IHC=== |
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