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→Epithelioid hemangioendothelioma: +IHC, remove obsolete website ref
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==Epithelioid hemangioendothelioma== | ==Epithelioid hemangioendothelioma== | ||
*Should not be confused with ''epithelioid hemangioma''. | *Should not be confused with ''[[epithelioid hemangioma]]''. | ||
===General=== | ===General=== | ||
*Malignant.<ref name=Ref_WMSP603>{{Ref WMSP|603}}</ref> | *Malignant.<ref name=Ref_WMSP603>{{Ref WMSP|603}}</ref> | ||
*Adults - wide age range. | |||
*Associated with oral contraceptives, vinyl chloride.<ref name=pmid20165548/> | |||
===Microscopic=== | ===Microscopic=== | ||
Features:<ref> | Features:<ref name=pmid20165548>{{Cite journal | last1 = Gupta | first1 = R. | last2 = Mathur | first2 = SR. | last3 = Gupta | first3 = SD. | last4 = Durgapal | first4 = P. | last5 = Iyer | first5 = VK. | last6 = Das | first6 = CJ. | last7 = Shalimar | first7 = SK. | last8 = Acharya | first8 = . | title = Hepatic epithelioid hemangioendothelioma: A diagnostic pitfall in aspiration cytology. | journal = Cytojournal | volume = 6 | issue = | pages = 25 | month = | year = 2010 | doi = 10.4103/1742-6413.58951 | PMID = 20165548 | URL = http://www.biomedsearch.com/nih/Hepatic-epithelioid-hemangioendothelioma-diagnostic-pitfall/20165548.html }}</ref> | ||
* | *Large epithelioid perivascular cells with: | ||
*Cytoplasmic vacuolation ( | **Abundant pale eosinophilic cytoplasm. | ||
***Cytoplasmic vacuolation (some cells). | |||
****May form lumen and have RBC within. | |||
**Vesicular nucleus with prominent nucleolus in some cells. | |||
*Tuft-like projections into capillaries. | *Tuft-like projections into capillaries. | ||
Image: | Image: | ||
*[http://en.wikipedia.org/wiki/File:Epithelioid_hemangioendothelioma_EHE.Image5.jpg Epithelioid hemangioendothelioma (WP)]. | *[http://en.wikipedia.org/wiki/File:Epithelioid_hemangioendothelioma_EHE.Image5.jpg Epithelioid hemangioendothelioma (WP)]. | ||
*[http://www.pathconsultddx.com/pathCon/largeImage?pii=S1559-8675%2806%2971574-1&figureId=fig1 Epithelioid hemangioendothelioma (pathconsultddx.com)]. | *[http://www.pathconsultddx.com/pathCon/largeImage?pii=S1559-8675%2806%2971574-1&figureId=fig1 Epithelioid hemangioendothelioma (pathconsultddx.com)]. | ||
===IHC=== | |||
Features:<ref name=pmid20165548>{{Cite journal | last1 = Gupta | first1 = R. | last2 = Mathur | first2 = SR. | last3 = Gupta | first3 = SD. | last4 = Durgapal | first4 = P. | last5 = Iyer | first5 = VK. | last6 = Das | first6 = CJ. | last7 = Shalimar | first7 = SK. | last8 = Acharya | first8 = . | title = Hepatic epithelioid hemangioendothelioma: A diagnostic pitfall in aspiration cytology. | journal = Cytojournal | volume = 6 | issue = | pages = 25 | month = | year = 2010 | doi = 10.4103/1742-6413.58951 | PMID = 20165548 | URL = http://www.biomedsearch.com/nih/Hepatic-epithelioid-hemangioendothelioma-diagnostic-pitfall/20165548.html }}</ref> | |||
*CD31 +ve. | |||
*CD34 +ve. | |||
*Factor VIII +ve. | |||
==See also== | ==See also== | ||