Difference between revisions of "Dermatopathology"

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348 bytes added ,  18:12, 2 September 2011
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| some classify this as '''benign'''; thought to be related to [[undifferentiated pleomorphic sarcoma]]
| some classify this as '''benign'''; thought to be related to [[undifferentiated pleomorphic sarcoma]]
| [http://dermatology.cdlib.org/141/case_reports/afx/1.jpg (cdlib.org)]<ref name=pmid18319023>{{Cite journal  | last1 = Vandergriff | first1 = TW. | last2 = Reed | first2 = JA. | last3 = Orengo | first3 = IF. | title = An unusual presentation of atypical fibroxanthoma. | journal = Dermatol Online J | volume = 14 | issue = 1 | pages = 6 | month =  | year = 2008 | doi =  | PMID = 18319023 }}</ref>  
| [http://dermatology.cdlib.org/141/case_reports/afx/1.jpg (cdlib.org)]<ref name=pmid18319023>{{Cite journal  | last1 = Vandergriff | first1 = TW. | last2 = Reed | first2 = JA. | last3 = Orengo | first3 = IF. | title = An unusual presentation of atypical fibroxanthoma. | journal = Dermatol Online J | volume = 14 | issue = 1 | pages = 6 | month =  | year = 2008 | doi =  | PMID = 18319023 }}</ref>  
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| Entity
| [[Merkel cell carcinoma]]
| Key histologic features
| neuroendocrine nuclear features (stippled chromatin, no nucleolus), scant cytoplasm
| Other features
| +/-nuclear moulding, usu. intermediate cell size
| Clinical
| Merkel cell polyomavirus associated, usu. head & neck or extremities
| Stains/IHC
| CK20+, EMA+
| DDx
| cutaneous [[Ewing sarcoma]], [[basal cell carcinoma]], (dermal) [[lymphoma]]
| Other
| rare, aggressive
| Image -->
| [http://www.bccancer.bc.ca/HPI/CE/cytotechnology/cytosleuthquiz/nongyne/ng12hist.htm (bccancer.bc.ca)]
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| Entity
| Entity
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