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Difference between revisions of "Non-malignant skin disease"
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Non-malignant skin disease (view source)
Revision as of 13:19, 2 September 2011
, 13:19, 2 September 2011→Granuloma annulare: split "granuloma annulare" into superficial and deep
(→Less common: more) |
(→Granuloma annulare: split "granuloma annulare" into superficial and deep) |
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===Microscopic=== | ===Microscopic=== | ||
Features:<ref name= | Divided into ''subcutaneous'' (superficial?) and ''interstitial'' (deep?). | ||
====Subcutaneous==== | |||
Features:<ref name=Ref_WMSP478>{{Ref WMSP|478}}</ref> | |||
*Dermal palisading granuloma around: | *Dermal palisading granuloma around: | ||
**Mucin - '''key feature''' | **Mucin - '''key feature''' | ||
***Loose/pale, paucicellular, eosinophilic. | ***Loose/pale, paucicellular, eosinophilic. | ||
** | **Necrotic debris. | ||
* | *Chronic inflammatory cells. | ||
Notes: | Notes: | ||
*There may be multiple small foci with intervening normal dermis. | *There may be multiple small foci with intervening normal dermis.<ref name=Ref_Derm51>{{Ref Derm|51}}</ref> | ||
DDx: | DDx: | ||
| Line 372: | Line 374: | ||
Images: | Images: | ||
*[http://www.dermaamin.com/site/histopathology-of-the-skin/61-i/1813-interstitial-granuloma-annulare-.html Granuloma annulare (dermaamin.com)]. | *[http://www.dermaamin.com/site/histopathology-of-the-skin/61-i/1813-interstitial-granuloma-annulare-.html Granuloma annulare (dermaamin.com)]. | ||
====Interstitial==== | |||
Features:<ref name=Ref_Derm51>{{Ref Derm|51}}</ref> | |||
*Dermal palisading granuloma around: | |||
**Necrotic collagen - '''key feature'''. | |||
**Mucin. | |||
***Loose/pale, paucicellular, eosinophilic. | |||
*+/-Eosinophils. | |||
Notes: | |||
*Histomorphologically similar to ''[[Rheumatoid nodule]]''. | |||
DDx: | |||
*Necrobiosis lipoidica - little mucin, no normal dermis between foci.<ref name=Ref_Derm51>{{Ref Derm|51}}</ref> | |||
==Keloid== | ==Keloid== | ||