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Difference between revisions of "Dermatopathology"
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→Pre-malignant/malignant
| Line 237: | Line 237: | ||
| [[squamous carcinoma]] | | [[squamous carcinoma]] | ||
| [http://commons.wikimedia.org/wiki/File:Actinic_Keratosis,_H%26E.jpg (WC)] | | [http://commons.wikimedia.org/wiki/File:Actinic_Keratosis,_H%26E.jpg (WC)] | ||
|- | |||
| [[Basal cell carcinoma]] | |||
| basaloid cells with peripheral palisading, artificial cleft | |||
| Other features | |||
| pearly, telangiectasia | |||
| none (???) | |||
| [[trichoepithelioma]] | |||
| assoc. [[nevoid basal cell carcinoma syndrome]], Bazex syndrome | |||
| Image | |||
|- | |||
| [[Squamous cell carcinoma]] | |||
| nuclear enlargement, eosinophilic cytoplasm, central nucleus | |||
| small nucleolus, intercellular bridges | |||
| flaky appearance | |||
| p63+, HMWK+ (???) | |||
| [[keratoacanathoma]] | |||
| Other | |||
| Image | |||
|- | |||
| [[Melanoma]] | |||
| nuclear atypia (nucleoli), spindle and/or epithelioid morphology | |||
| mitoses (esp. deep), +/-pigment, +/-nested arch., asymmetry, upward spread (into epidermis), epithelioid m. deep | |||
| ABCD = Asymmetry, Borders poor demarc., Dolour dark, Diameter large | |||
| S100+, Melan A+, HMB-45+, microphthalmia+, tyrosinase+ | |||
| [[melanocytic lesions]] | |||
| may be familial, [[dysplastic nevus]] | |||
| [http://en.wikipedia.org/wiki/File:Malignant_melanoma_%281%29_at_thigh_Case_01.jpg (WC)] | |||
|- <!-- | |- <!-- | ||
| [[Basal cell carcinoma]] | | [[Basal cell carcinoma]] | ||