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Difference between revisions of "Melanocytic lesions"
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more dermal nevus here
(→Spitz nevus: Camino) |
(more dermal nevus here) |
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*"Maturation" in the context of melanocytic lesions ''means'' (1) the cells get smaller with depth, (2) cells are less mitotic with depth. | *"Maturation" in the context of melanocytic lesions ''means'' (1) the cells get smaller with depth, (2) cells are less mitotic with depth. | ||
==Dermal nevus== | |||
*[[AKA]] ''mole''. | |||
===General=== | |||
*Think ''melanoma''. | |||
Clinical: ''ABCD'' = asymmetric, borders (irregular), colour (black), diameter (large). | |||
===Microscopic=== | |||
Features:<ref>need ref</ref> | |||
*Symmetrical lesion. | |||
*"Matures" with depth - less cellular, less atypia. | |||
*No destruction of surrounding structures. | |||
*Only in dermis '''key feature'''. | |||
**Otherwise it is something else, e.g. ''dermal nevus'', ''junctional nevus''. | |||
===Microscopic=== | |||
*Basaloid cells mixed with squamous cells. | |||
*Keratin-filled invaginations. | |||
*Horn cysts - intraepidermal, brown globule-like structures. | |||
**Melanocytes at the dermoepidermal junction.<ref>URL: [http://emedicine.medscape.com/article/1059477-overview http://emedicine.medscape.com/article/1059477-overview].</ref> | |||
==Spitz nevus== | ==Spitz nevus== | ||