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(→Pheochromocytoma: 10s) |
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Line 144: | Line 144: | ||
*Tumour arises from medulla | *Tumour arises from medulla | ||
Clinical | Memory device - the rule of 10s:<ref name=Ref_PCPBoD8_586>{{Ref PCPBoD8|586}}</ref> | ||
*10% extra-adrenal (e.g. organ of Zuckerkandl). | |||
*10% bilateral. | |||
*10% malignant. | |||
*10% no hypertension. | |||
*25% associated with [[multiple endocrine neoplasia]] 2a and 2b. | |||
====Clinical==== | |||
*Classic finding: hypertension. | *Classic finding: hypertension. | ||
*Paroxysms (i.e. episodes) of tachycardia, headache, anxiety, hypertension. | *Paroxysms (i.e. episodes) of tachycardia, headache, anxiety, hypertension. | ||
Line 151: | Line 158: | ||
*Vanillylmandelic acid (VMA). | *Vanillylmandelic acid (VMA). | ||
*Metanephrines. | *Metanephrines. | ||
===Microscopic=== | ===Microscopic=== |
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