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Image: | Image: | ||
*[http://commons.wikimedia.org/wiki/File:Rete_testis_high_mag.jpg Rete testis (WC)]. | |||
*[http://www.webpathology.com/image.asp?case=27&n=5 Rete testis (webpathology.com)]. | *[http://www.webpathology.com/image.asp?case=27&n=5 Rete testis (webpathology.com)]. | ||
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==Intratubular germ cell neoplasia== | ==Intratubular germ cell neoplasia== | ||
===General=== | |||
*Considered the precursor lesion for germ cell tumours. | *Considered the precursor lesion for germ cell tumours. | ||
*Not all germ cell tumours (GCTs) arise from ''intratubular germ cell neoplasia''. | *Not all germ cell tumours (GCTs) arise from ''intratubular germ cell neoplasia''. | ||
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*Mitoses - common. | *Mitoses - common. | ||
*Nuclei overlap. | *Nuclei overlap. | ||
*Vesicular nuclei (clear, empty appearing nuclei) - '''key feature'''. | |||
*Nucleoli - '''key feature'''. | |||
*Variable architecture: | *Variable architecture: | ||
**Tubulopapillary. | **Tubulopapillary. | ||
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**Solid. | **Solid. | ||
**Embryoid bodies - ball of cells in surrounded by empty space on three sides. | **Embryoid bodies - ball of cells in surrounded by empty space on three sides. | ||
*Necrosis - common. | |||
**Not present in seminoma. | |||
Notes: | Notes: |
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