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Difference between revisions of "Gastrointestinal tract polyps"
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Gastrointestinal tract polyps (view source)
Revision as of 15:02, 13 August 2011
, 15:02, 13 August 2011→Traditional adenoma: more
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***The surface is more hyperchromatic (more blue). | ***The surface is more hyperchromatic (more blue). | ||
***The base is more mature (more globlet cells, no nuclear changes -- less blue). | ***The base is more mature (more globlet cells, no nuclear changes -- less blue). | ||
Images: | |||
*[http://commons.wikimedia.org/wiki/File:Tubular_adenoma_high_mag.jpg Small tubular adenoma - high mag. (WC)]. | |||
*[http://commons.wikimedia.org/wiki/File:Tubular_adenoma_2_intermed_mag.jpg Tubular adenoma - intermed. mag. (WC)]. | |||
*[http://commons.wikimedia.org/wiki/File:Tubulovillous_adenoma.jpg Tubulovillous adenoma (WC)]. | |||
===Typing=== | ===Typing=== | ||
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Note 1:<ref name=pbod860/> | Note 1:<ref name=pbod860/> | ||
*Most villous adenomas are sessile, i.e. flat.<ref name=emed_va>[http://emedicine.medscape.com/article/170283-overview http://emedicine.medscape.com/article/170283-overview]</ref> | *Most villous adenomas are sessile, i.e. flat.<ref name=emed_va>URL: [http://emedicine.medscape.com/article/170283-overview http://emedicine.medscape.com/article/170283-overview].</ref> | ||
*Tubular adenomas tend to be pedunculated, i.e. have a stalk. | *Tubular adenomas tend to be pedunculated, i.e. have a stalk. | ||
*Villous adenomas have a worse prognosis and warrant closer follow-up. | *Villous adenomas have a worse prognosis and warrant closer follow-up. | ||
*One needs only to remember the criteria for ''tubular adenomas'' and ''villous adenomas'', as tubulovillous adenomas are what is left over. | *One needs only to remember the criteria for ''tubular adenomas'' and ''villous adenomas'', as tubulovillous adenomas are what is left over. | ||
**Tubular adenomas >75% tubular, Villous adenoma >=50% villous. | **Tubular adenomas >75% tubular, Villous adenoma >=50% villous. | ||
* | *Historically, there were different definitions for tubular adenoma, tubulovillous adenoma, and villous adenomas.<ref name=emed_va/> | ||
**Health Organization (WHO) criteria: villous adenomas >80% villous architecture. | **Health Organization (WHO) criteria: villous adenomas >80% villous architecture. | ||
Note 2: | Note 2: | ||
*There is no formal definition of "villous" architecture.<ref>R. Riddell. 12 August 2011.</ref> | |||
**[[VL]] suggests: slender finger-like projections with length-to-width ratio greater than 4. | |||
Note 3: | |||
*The term ''tubular adenoma'' is used in different contexts; it should not be confused with [[Sertoli cell nodule]] ([[AKA]] ''testicular tubular adenoma''). | *The term ''tubular adenoma'' is used in different contexts; it should not be confused with [[Sertoli cell nodule]] ([[AKA]] ''testicular tubular adenoma''). | ||