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Difference between revisions of "Germ cell tumours"
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→Teratoma
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==Teratoma== | ==Teratoma== | ||
===General=== | ===General=== | ||
* | *May be benign of malignant. | ||
*Are supposed to consists of all three [[germ layers]] - this is not always true. | |||
====Classification==== | |||
#Mature. | |||
#*Common in females, not seen in males. | |||
#*Usually benign; however, mature component may give rise to a malignancy like elsewhere in the body. | |||
#**Most common malignancy arising from a mature teratoma: [[squamous cell carcinoma]]. | |||
#Immature. | |||
#*Uncommon. | |||
#*Malignant. | |||
#Monodermal. | |||
#*Rare. | |||
#*Highly specialized. | |||
===Mature=== | |||
Features - three germ cell layers (usually):<ref>{{cite book |author=Moore, Keith L.; Persaud, T.V.N.|title=The Developing Human: Clinically Oriented Embryology |publisher=Saunders |location= |year=2002 |pages= 83 |edition=7th |isbn=978-0721694122 |oclc= |doi= |accessdate=}}</ref> | |||
*#Endoderm: | *#Endoderm: | ||
*#*Skin, CNS. | *#*Skin, (mature) CNS. | ||
*#Mesoderm: | *#Mesoderm: | ||
*#*Muscle, bone, connective tissue, blood. | *#*Muscle, bone, connective tissue, blood. | ||
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*#*Internal organs. | *#*Internal organs. | ||
Note: | |||
*May consist of skin only - in which case it is commonly called a ''dermoid''. | |||
Images: | |||
*[http://commons.wikimedia.org/wiki/File:Teratoma_2_low_mag.jpg Mature teratoma - low mag. (WC)]. | |||
*[http://commons.wikimedia.org/wiki/File:Teratoma_2_high_mag.jpg Mature teratoma - high mag. (WC)]. | |||
===Immature=== | ===Immature=== | ||
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**Synaptophysin +ve. | **Synaptophysin +ve. | ||
=== | ===Monodermal teratomas=== | ||
====Struma ovarii==== | ====Struma ovarii==== | ||
Features: | Features: | ||