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Difference between revisions of "Liver neoplasms"
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→Metastases
(→Hepatocellular carcinoma: moer) |
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*Clear cell variant of HCC may be misdiagnosed as metastatic clear cell carcinoma. | *Clear cell variant of HCC may be misdiagnosed as metastatic clear cell carcinoma. | ||
*Interhepatic cholangiocarcinoma is an adenocarcinoma - it may look like a metastatic lesion. | *Interhepatic cholangiocarcinoma is an adenocarcinoma - it may look like a metastatic lesion. | ||
<br> | |||
Further reading: | Further reading: | ||
*{{Cite journal | last1 = Anders | first1 = RA. | last2 = Kamel | first2 = IR. | title = Biopsy considerations in the diagnosis of hepatic masses. | journal = Clin Gastroenterol Hepatol | volume = 5 | issue = 5 | pages = 541-4 | month = May | year = 2007 | doi = 10.1016/j.cgh.2007.02.028 | PMID = 17478344 }} | |||
===Gross pathology/radiology=== | ===Gross pathology/radiology=== | ||
*Multifocal or solitary. | *Multifocal or solitary. | ||
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===Microscopic=== | ===Microscopic=== | ||
*Histologic features are dependent on primary and degree of differentiation. | *Histologic features are dependent on primary and degree of differentiation. | ||
The classic liver metastasis ([[colorectal carcinoma]]): | |||
*Gland forming columnar shaped cells with pseudostratified hyperchromatic cigar-shaped nuclei. | |||
Image: [http://commons.wikimedia.org/wiki/File:Adenocarcinoma_liver_metastasis.jpg Liver metastasis - adenocarcinoma (WC)]. | <br> | ||
Image: | |||
*[http://commons.wikimedia.org/wiki/File:Adenocarcinoma_liver_metastasis.jpg Liver metastasis - adenocarcinoma, not obviously CRC (WC)]. | |||
===IHC=== | ===IHC=== | ||