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m (→Grossing) |
(→Bowel ischemia: more) |
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==Bowel ischemia== | ==Bowel ischemia== | ||
=== | ===General=== | ||
* | *[[Atherosclerosis]]. | ||
*Radiation. | |||
===Gross=== | ===Gross=== | ||
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**... anything that causes severe mucosal injury. | **... anything that causes severe mucosal injury. | ||
====Radiologic correlate==== | |||
*Bowel wall thickening. | |||
==Microscopic== | |||
Features:<ref>Kirsch, R. 8 August 2011.</ref> | |||
*Crypt loss. | |||
*Lamina propria fibrosis. | |||
*Submucosa fibrosis. | |||
Pseudomembranes (microscopic):<ref name=Ref_PBoD837-8>{{Ref PBoD|837-8}}</ref> | |||
*Loss of surf. epithelium. | *Loss of surf. epithelium. | ||
*[[PMN]]s in lamina propria. | *[[PMN]]s in lamina propria. | ||
*+/- capillary fibrin thrombi. | *+/- capillary fibrin thrombi. | ||
Note: | |||
*Pseudomembranes arise from the crypts. | |||
Images: | |||
*[http://commons.wikimedia.org/wiki/File:Colonic_pseudomembranes_low_mag.jpg Micrograph of pseudomembranes - low mag. (wikimedia.org)]. | *[http://commons.wikimedia.org/wiki/File:Colonic_pseudomembranes_low_mag.jpg Micrograph of pseudomembranes - low mag. (wikimedia.org)]. | ||
*[http://commons.wikimedia.org/wiki/File:Colonic_pseudomembranes_intermed_mag.jpg Micrograph of pseudomembranes - intermed. mag. (wikimedia.org)]. | *[http://commons.wikimedia.org/wiki/File:Colonic_pseudomembranes_intermed_mag.jpg Micrograph of pseudomembranes - intermed. mag. (wikimedia.org)]. | ||
DDx: | |||
*[[IBD]]. | |||
*Radiation. | |||
*Toxins/drugs. | |||
==Angiodysplasia== | ==Angiodysplasia== |
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