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Difference between revisions of "Pancreas"
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→Solid pseudopapillary tumour
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==Solid pseudopapillary tumour== | ==Solid pseudopapillary tumour== | ||
*[[AKA]] ''solid pseudopapillary neoplasm''. | |||
===General=== | ===General=== | ||
*Obscure cell of origin. | *Obscure cell of origin. | ||
*Considered low grade, i.e. prognosis is usually good. | *Considered low grade, i.e. prognosis is usually good. | ||
===Epidemiology=== | ====Epidemiology==== | ||
Features:<ref name=Ref_GLP493>{{Ref GLP|493}}</ref> | Features:<ref name=Ref_GLP493>{{Ref GLP|493}}</ref> | ||
*Usually females (M:F=1:9). | *Usually females (M:F=1:9). | ||
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===IHC=== | ===IHC=== | ||
Features:<ref>{{cite journal |author=Serra S, Chetty R |title=Revision 2: an immunohistochemical approach and evaluation of solid pseudopapillary tumour of the pancreas |journal=J. Clin. Pathol. |volume=61 |issue=11 |pages=1153–9 |year=2008 |month=November |pmid=18708424 |doi=10.1136/jcp.2008.057828 |url=http://jcp.bmj.com/content/61/11/1153}}</ref> | Features:<ref name=pmid18708424>{{cite journal |author=Serra S, Chetty R |title=Revision 2: an immunohistochemical approach and evaluation of solid pseudopapillary tumour of the pancreas |journal=J. Clin. Pathol. |volume=61 |issue=11 |pages=1153–9 |year=2008 |month=November |pmid=18708424 |doi=10.1136/jcp.2008.057828 |url=http://jcp.bmj.com/content/61/11/1153}}</ref> | ||
*Beta-catenin +ve ~100% (cytoplasmic & nuclear). | *Beta-catenin +ve ~100% (cytoplasmic & nuclear). | ||
*E-cadherin +ve ~100% (cytoplasmic), -ve (membrane); antibody dependent. | *E-cadherin +ve ~100% (cytoplasmic), -ve (membrane); antibody dependent. | ||