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Difference between revisions of "Kidney tumours"
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*Grade 1: no nucleoli, near 'normal' appearance. | *Grade 1: no nucleoli, near 'normal' appearance. | ||
*Grade 2: finely granular chromatin (key feature), no nuclei visible with 10x objective lens. | *Grade 2: finely granular chromatin (key feature), no nuclei visible with 10x objective lens. | ||
*Grade 3: nucleoli seen easily (key feature). | *Grade 3: [[nucleoli]] seen easily (key feature). | ||
*Grade 4: prominent pleomorphism (key feature), hyperchromasia, macronucleoli. | *Grade 4: prominent pleomorphism (key feature), hyperchromasia, [[macronucleoli]]. | ||
Note: Most tumours are grade 2 & 3. | Note: Most tumours are grade 2 & 3. | ||
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*Small uniform cells with: | *Small uniform cells with: | ||
**Fine chromatin. | **Fine chromatin. | ||
**No apparent [[ | **No apparent [[nucleolus]]. | ||
**A relatively smooth nuclear membrane. | **A relatively smooth nuclear membrane. | ||
*Variable architecture - may be sheets or ductal. | *Variable architecture - may be sheets or ductal. | ||