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Difference between revisions of "Fibroblastic/myofibroblastic tumours"
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Fibroblastic/myofibroblastic tumours (view source)
Revision as of 19:06, 5 August 2011
, 19:06, 5 August 2011→Hemangiopericytoma: re-arr.
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*Oncogenic osteomalacia - assoc. with hemangiopericytoma.<ref name=emed1255879ov>URL: [http://emedicine.medscape.com/article/1255879-overview http://emedicine.medscape.com/article/1255879-overview]. Accessed on: 2 May 2010.</ref> | *Oncogenic osteomalacia - assoc. with hemangiopericytoma.<ref name=emed1255879ov>URL: [http://emedicine.medscape.com/article/1255879-overview http://emedicine.medscape.com/article/1255879-overview]. Accessed on: 2 May 2010.</ref> | ||
===Presentation=== | ====Presentation==== | ||
*Usually painless mass, slow enlargement. | *Usually painless mass, slow enlargement. | ||
===Radiology=== | |||
*Intramedullary lytic mass. | *Intramedullary lytic mass. | ||
*May be well-circumscribed. | *May be well-circumscribed. | ||
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May be worked-up with angiography to distinguish from a [[vascular malformation]].<ref name=emed1255879dx>URL: [http://emedicine.medscape.com/article/1255879-diagnosis http://emedicine.medscape.com/article/1255879-diagnosis]. Accessed on: 2 May 2010.</ref> | May be worked-up with angiography to distinguish from a [[vascular malformation]].<ref name=emed1255879dx>URL: [http://emedicine.medscape.com/article/1255879-diagnosis http://emedicine.medscape.com/article/1255879-diagnosis]. Accessed on: 2 May 2010.</ref> | ||
===Location=== | ====Location==== | ||
*Usually extremities - femur or proximal tibial.<ref name=emed1255879ov>URL: [http://emedicine.medscape.com/article/1255879-overview http://emedicine.medscape.com/article/1255879-overview]. Accessed on: 2 May 2010.</ref> | *Usually extremities - femur or proximal tibial.<ref name=emed1255879ov>URL: [http://emedicine.medscape.com/article/1255879-overview http://emedicine.medscape.com/article/1255879-overview]. Accessed on: 2 May 2010.</ref> | ||
=== | ===Microscopic=== | ||
Features:<ref name=emed1255879dx>URL: [http://emedicine.medscape.com/article/1255879-diagnosis http://emedicine.medscape.com/article/1255879-diagnosis]. Accessed on: 2 May 2010.</ref> | Features:<ref name=emed1255879dx>URL: [http://emedicine.medscape.com/article/1255879-diagnosis http://emedicine.medscape.com/article/1255879-diagnosis]. Accessed on: 2 May 2010.</ref> | ||
*Hypervascular lesion - '''key diagnostic feature'''.<ref name=enzinger>Enzinger & Weiss's Soft Tissue Tumors. 4th Ed. PP.1007-13. ISBN 0-323-01200-0.</ref> | *Hypervascular lesion - '''key diagnostic feature'''.<ref name=enzinger>Enzinger & Weiss's Soft Tissue Tumors. 4th Ed. PP.1007-13. ISBN 0-323-01200-0.</ref> | ||
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***Cells may "onion-skin" around thin blood vessels. | ***Cells may "onion-skin" around thin blood vessels. | ||
*Spindle or ovoid shaped cells in nests or sheets. | *Spindle or ovoid shaped cells in nests or sheets. | ||
DDx: | |||
*Other vascular tumours. | |||
*Vascular malformations. | |||
*Synovial sarcoma. | |||
===IHC=== | ===IHC=== | ||
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*EMA -ve. | *EMA -ve. | ||
*S100 -ve. | *S100 -ve. | ||
==Desmoplastic fibroblastoma== | ==Desmoplastic fibroblastoma== | ||