Difference between revisions of "Prostate gland"

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163 bytes added ,  19:59, 4 June 2010
(→‎Gleason grading system: more details on gleason scoring)
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====Gleason grading system====
====Gleason grading system====
*Score range: 2-10.
*Score range: 2-10.
*Reported as: (primary pattern) + (secondary pattern ''or'' tertiary pattern with the highest grade) = sum.
*Reported as on biopsy as: (primary pattern) + (secondary pattern ''or'' tertiary pattern with the highest grade) = sum.
**e.g. ''Gleason grade 3+4=7'' means: pattern 3 is present and dominant, pattern 4 is the remainder of the tumour but present in a lesser amount than pattern 3.
**e.g. ''Gleason grade 3+4=7'' means: pattern 3 is present and dominant, pattern 4 is the remainder of the tumour - but present in a lesser amount than pattern 3.
**If a biopsy has 80% pattern 4, 15.1% pattern 3 and 4.9% pattern 5... it would be reported as: 3+5=8.
*Reported as on prostatectomies as: (primary pattern) + (secondary pattern) = sum, (tertiary pattern)
***If the same percentages are seen on a prostatectomy the report would be: 4+3=7 with tertiary 5.


Tertiary Gleason pattern - definition: a pattern that is seen in than 5% of the tumour (volume), that is higher than the two dominant patterns.<ref>GUP P.72.</ref>
*Tertiary Gleason pattern - definition: a pattern that is seen in than 5% of the tumour (volume), that is higher grade than the two dominant patterns.<ref>GUP P.72.</ref>
*The presence of a tertiary patterns adversely affect the prognosis; however, the prognosis is not as bad as when the tertiary pattern is the secondary pattern, i.e. 3+4 tertiary 5 has a better prognosis than 3+5 (with some small amount of pattern 4).<ref>GUP P.72.</ref>
**The presence of a tertiary patterns adversely affect the prognosis; however, the prognosis is not as bad as when the tertiary pattern is the secondary pattern, i.e. 3+4 tertiary 5 has a better prognosis than 3+5 (with some small amount of pattern 4).<ref>GUP P.72.</ref>
 
Examples:
*A biopsy has 80% pattern 4, 15.1% pattern 3 and 4.9% pattern 5... it would be reported as: 4+5=9.
*A prostatectomy has 80% pattern 4, 15.1% pattern 3 and 4.9% pattern 5... it would be reported as: 4+3=7 with tertiary pattern 5.


====Gleason pattern 1 & 2====  
====Gleason pattern 1 & 2====  
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