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Difference between revisions of "Testis"
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==Spermatocytic seminoma== | ==Spermatocytic seminoma== | ||
===Microscopy<ref>{{cite book |author=Cotran, Ramzi S.; Kumar, Vinay; Fausto, Nelson; Nelso Fausto; Robbins, Stanley L.; Abbas, Abul K. |title=Robbins and Cotran pathologic basis of disease |publisher=Elsevier Saunders |location=St. Louis, Mo |year=2005 |pages= |edition=7th |isbn=0-7216-0187-1 |oclc= |doi= |accessdate=}}</ref> | ===General=== | ||
*Rare tumour. | |||
*Only one case of metastases in 200 cases.<ref name=pmid7927308>{{cite journal |author=Eble JN |title=Spermatocytic seminoma |journal=Hum. Pathol. |volume=25 |issue=10 |pages=1035–42 |year=1994 |month=October |pmid=7927308 |doi= |url=}}</ref> | |||
*Orchiectomy is curative. | |||
*Not reported/found in females.<ref name=pmid7927308/> | |||
===Epidemiology=== | |||
*Does NOT arise from ''intratubular germ cell neoplasia'' (ITGCN)<ref>{{cite journal |author=Müller J, Skakkebaek NE, Parkinson MC |title=The spermatocytic seminoma: views on pathogenesis |journal=Int. J. Androl. |volume=10 |issue=1 |pages=147–56 |year=1987 |month=February |pmid=3583416 |doi= 10.1111/j.1365-2605.1987.tb00176.x|url=}}</ref> - '''not''' considered a subtype of seminoma. | |||
===Microscopy=== | |||
Features:<ref>{{cite book |author=Cotran, Ramzi S.; Kumar, Vinay; Fausto, Nelson; Nelso Fausto; Robbins, Stanley L.; Abbas, Abul K. |title=Robbins and Cotran pathologic basis of disease |publisher=Elsevier Saunders |location=St. Louis, Mo |year=2005 |pages= |edition=7th |isbn=0-7216-0187-1 |oclc= |doi= |accessdate=}}</ref> | |||
*Population of three cells. | *Population of three cells. | ||
**Small cells - look like secondary spermatocytes. | **Small cells - look like secondary spermatocytes. | ||
**Medium cells with nucleoli. | **Medium cells with nucleoli. | ||
**Large cells. | ***Filamentous chromatin (AKA ''spireme chromatin'').<ref name=pmid7927308>{{cite journal |author=Eble JN |title=Spermatocytic seminoma |journal=Hum. Pathol. |volume=25 |issue=10 |pages=1035–42 |year=1994 |month=October |pmid=7927308 |doi= |url=}}</ref> | ||
**Large cells | |||
***Filamentous chromatin. | |||
*Mucoid lakes. | |||
*Intratubular spread. | |||
Notes: | |||
* | *''Spireme'' = tangle of filaments in prophase mitosis.<ref>URL: [http://www.thefreedictionary.com/spireme http://www.thefreedictionary.com/spireme]. Accessed on: 4 June 2010.</ref> | ||
==Yolk sac tumour== | ==Yolk sac tumour== | ||