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Difference between revisions of "Lymph node pathology"
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→Overview in a table: wikify
(→Overview in a table: wikify) |
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| tingible body macrophages, normal dark/light GC pattern | | tingible body macrophages, normal dark/light GC pattern | ||
| BCL2 -ve | | BCL2 -ve | ||
| infection (Toxoplasmosis, [[HIV]]/AIDS), [[Hodgkin's lymphoma]] | | infection ([[Toxoplasmosis]], [[HIV]]/AIDS), [[Hodgkin's lymphoma]] | ||
| image ? | | image ? | ||
|- | |- | ||
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| [http://commons.wikimedia.org/wiki/File:Progressive_transformation_of_germinal_centres_-1-_very_low_mag.jpg], [http://commons.wikimedia.org/wiki/File:Progressive_transformation_of_germinal_centres_-1-_low_mag.jpg] | | [http://commons.wikimedia.org/wiki/File:Progressive_transformation_of_germinal_centres_-1-_very_low_mag.jpg], [http://commons.wikimedia.org/wiki/File:Progressive_transformation_of_germinal_centres_-1-_low_mag.jpg] | ||
|- | |- | ||
| Toxoplasmosis | | [[Toxoplasmosis]] | ||
| large follicles; epithelioid cells perifollicular & intrafollicular | | large follicles; epithelioid cells perifollicular & intrafollicular | ||
| reactive GCs, monocytoid cell clusters, epithelioid cells | | reactive GCs, monocytoid cell clusters, epithelioid cells | ||
| IHC for toxoplasma | | IHC for toxoplasma | ||
| NSRFH, HIV/AIDS, Hodgkin's lymphoma | | NSRFH, HIV/AIDS, [[Hodgkin's lymphoma]] | ||
| [http://commons.wikimedia.org/wiki/File:Toxoplasmosis_lymphadenopathy_-_low_mag.jpg], [http://commons.wikimedia.org/wiki/File:Toxoplasmosis_lymphadenopathy_-b-_high_mag.jpg] | | [http://commons.wikimedia.org/wiki/File:Toxoplasmosis_lymphadenopathy_-_low_mag.jpg], [http://commons.wikimedia.org/wiki/File:Toxoplasmosis_lymphadenopathy_-b-_high_mag.jpg] | ||
|- | |- | ||
| Kikuchi disease (histiocystic necrotizing lymphadenitis) | | [[Kikuchi disease]] (histiocystic necrotizing lymphadenitis) | ||
| No PMNs | | No PMNs | ||
| histiocytes, [[necrosis]] | | histiocytes, [[necrosis]] | ||
| Line 68: | Line 68: | ||
| [http://commons.wikimedia.org/wiki/File:Kimura_disease_-_very_high_mag.jpg] | | [http://commons.wikimedia.org/wiki/File:Kimura_disease_-_very_high_mag.jpg] | ||
|- | |- | ||
| Langerhans cell histiocytosis | | [[Langerhans cell histiocytosis]] | ||
| abundant histiocytes with reniform nuclei | | abundant histiocytes with reniform nuclei | ||
| often prominent eosinophilia | | often prominent eosinophilia | ||
| Line 89: | Line 89: | ||
| [http://commons.wikimedia.org/wiki/File:Systemic_lupus_erythematosus_lymphadenopathy_-_high_mag.jpg] | | [http://commons.wikimedia.org/wiki/File:Systemic_lupus_erythematosus_lymphadenopathy_-_high_mag.jpg] | ||
|- | |- | ||
| Castleman disease, hyaline vascular variant | | [[Castleman disease]], hyaline vascular variant | ||
| thick mantle cell layer with laminar appearance ("onion skin" layering) | | thick mantle cell layer with laminar appearance ("onion skin" layering) | ||
| hyaline (pink crap), lollipops (large vessels into GC), no mitoses in GC | | hyaline (pink crap), lollipops (large vessels into GC), no mitoses in GC | ||