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Difference between revisions of "Prostate gland"
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→Cancer: more
(→Criteria as a list: more) |
(→Cancer: more) |
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===Low power features=== | ===Low power features=== | ||
*Architecture is the key to diagnosing low grade cancer. | *Architecture is the '''key''' to diagnosing low grade cancer. | ||
**Back-to-back glands or crowding of glands -- think low grade cancer (Gleason pattern 3). | **Back-to-back glands or crowding of glands -- think low grade cancer (Gleason pattern 3). | ||
**Sharp transition between gland border and lumen. | **Sharp transition between gland border and lumen. | ||
***Loss of epithelial folding at the epithelium-gland lumen interface - "punched-out" appearance. | ***Loss of epithelial folding at the epithelium-gland lumen interface - "punched-out" appearance. | ||
**Eosinophilic | **Eosinophilic debris within the gland lumen (pink amorphous secretions, intraluminal crystalloid). | ||
**Blue-tinged acellular material within the gland lumen (mucin) -- uncommon. | |||
===High power features=== | ===High power features=== | ||
*Nuclei. | *Nuclei. | ||
**Hyperchromatic nuclei (like in HGPIN). | **Hyperchromatic nuclei (like in HGPIN). | ||
**Nuclear | **Nuclear enlargement. | ||
***Difficult to appreciate (if cancer isn't side-by-side with normal prostate). | ***Difficult to appreciate (if cancer isn't side-by-side with normal prostate). | ||
***Difficult to see if not on high power. | ***Difficult to see if not on high power. | ||