Difference between revisions of "Small cell lymphomas"

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|-
| Mantle cell lymphoma
| Mantle cell lymphoma
| Mantle zone
| mantle zone
| Small
| small
| CD5+, CD23-, CD43+, cyclin D1+<ref name=Ref_Lester95>{{Ref Lester|95}}</ref>
| CD5+, CD23-, CD43+, cyclin D1+<ref name=Ref_Lester95>{{Ref Lester|95}}</ref>
| t(11;14)(q13;q32) BCL1/IGH<ref>URL: [http://atlasgeneticsoncology.org/Anomalies/t1114ID2021.html http://atlasgeneticsoncology.org/Anomalies/t1114ID2021.html]. Accessed on: 10 August 2010.</ref> (also IGH/BCL1<ref>URL: [http://www.wipo.int/patentscope/search/en/WO2010059499 http://www.wipo.int/patentscope/search/en/WO2010059499]. Accessed on: 26 May 2011.</ref>)
| t(11;14)(q13;q32) BCL1/IGH<ref>URL: [http://atlasgeneticsoncology.org/Anomalies/t1114ID2021.html http://atlasgeneticsoncology.org/Anomalies/t1114ID2021.html]. Accessed on: 10 August 2010.</ref> (also IGH/BCL1<ref>URL: [http://www.wipo.int/patentscope/search/en/WO2010059499 http://www.wipo.int/patentscope/search/en/WO2010059499]. Accessed on: 26 May 2011.</ref>)
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| Marginal zone lymphoma (includes MALT)
| Marginal zone lymphoma (includes MALT)
| Marginal zone
| [[lymph node|marginal zone]], [[spleen]], GI tract
| Small
| small
| CD21+, CD11c+, CD5-, CD23-<ref name=Ref_Lester95>{{Ref Lester|95}}</ref>
| CD21+, CD11c+, CD5-, CD23-<ref name=Ref_Lester95>{{Ref Lester|95}}</ref>
| t(11;18)(q21;q21) / API2‐MALT1, t(14;18)(q32;q21) / IGH‐MALT1, t(1;14)(p22;q32) / IGH‐BCL10<ref name=pmid16950858>{{cite journal |author=Bacon CM, Du MQ, Dogan A |title=Mucosa-associated lymphoid tissue (MALT) lymphoma: a practical guide for pathologists |journal=J. Clin. Pathol. |volume=60 |issue=4 |pages=361–72 |year=2007 |month=April |pmid=16950858 |pmc=2001121 |doi=10.1136/jcp.2005.031146 |url=}}</ref>
| t(11;18)(q21;q21) / API2‐MALT1, t(14;18)(q32;q21) / IGH‐MALT1, t(1;14)(p22;q32) / IGH‐BCL10<ref name=pmid16950858>{{cite journal |author=Bacon CM, Du MQ, Dogan A |title=Mucosa-associated lymphoid tissue (MALT) lymphoma: a practical guide for pathologists |journal=J. Clin. Pathol. |volume=60 |issue=4 |pages=361–72 |year=2007 |month=April |pmid=16950858 |pmc=2001121 |doi=10.1136/jcp.2005.031146 |url=}}</ref>


| classical GI lymphomas
| classical GI lymphoma
| Other
| subtypes: extranodal marginal zone lymphoma ([[AKA]] MALT lymphoma), SMZL, nodal marginal zone lymphoma
|-
|-
| Precursor B cell lymphoblastic lymphoma/leukemia
| Precursor B cell lymphoblastic lymphoma/leukemia
| Location ?
| location ?
| Small
| small
| CD10+, CD5-, TdT+, CD99+<ref name=Ref_Lester95>{{Ref Lester|95}}</ref>
| CD10+, CD5-, TdT+, CD99+<ref name=Ref_Lester95>{{Ref Lester|95}}</ref>
| t(9;22), others
| t(9;22), others
| good prognosis (?)
| good prognosis (?)
| Other ?
| other ?
|-
|-
| B cell small lymphocytic lymphoma /<br>chronic lymphocytic leukemia
| B cell small lymphocytic lymphoma /<br>chronic lymphocytic leukemia
| Location ?
| location ?
| Small
| Small
| CD5+, CD23+, CD43+, cyclin D1-
| CD5+, CD23+, CD43+, cyclin D1-
| Translocations ?
| translocations ?
| good prognosis / indolent course
| good prognosis / indolent course
| Other ?
| other ?
|- <!--
|- <!--
| Name/entity ?
| Name/entity ?
| Location ?
| location ?
| Size of cells ?
| size of cells ?
| IHC ?
| IHC ?
| Translocations ?
| translocations ?
| Clinical ?
| clinical ?
| Other ? -->
| other ? -->
|}
|}


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! IHC
! IHC
! Translocations
! Translocations
! Clinical
! Clinical  
! Other
! Other
|-
|-
| [[Burkitt's lymphoma]]
| [[Burkitt's lymphoma]]
| Follicle
| follicle
| Large cells
| large cells
| CD10, BCL6
| CD10, BCL6
| t(8;14) (q24;q32)  
| t(8;14) (q24;q32)  
| Rapid growth
| rapid growth
| "Starry sky"
| "starry sky"
|-
|-
| [[Diffuse large B cell lymphoma]]
| [[Diffuse large B cell lymphoma]]
| Follicle (?)
| follicle (?)
| Large 4-5X of lymphocyte
| Large 4-5X of lymphocyte
| MIB-1 >40%
| MIB-1 >40%
| none/like follicular l.
| none/like follicular l.
| Poor prognosis
| poor prognosis
| Common among lymphomas
| common among lymphomas
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