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(/* DDx of meningioma & IHC{{cite journal |author=Hahn HP, Bundock EA, Hornick JL |title=Immunohistochemical staining for claudin-1 can help distinguish meningiomas from histologic mimics |journal=Am. J. Clin. Pathol. |volume=125 |issue=2 |pages=203) |
m (→Histologic grading: more) |
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Line 85: | Line 85: | ||
*#*Protrusion of meningioma into brain. | *#*Protrusion of meningioma into brain. | ||
*#**Meninogioma with entraped GFAP +ve tissue. | *#**Meninogioma with entraped GFAP +ve tissue. | ||
*#Atypical meningioma (by histomorphology). | *#Atypical meningioma (by histomorphology) - either ''A'' or ''B''. | ||
*#*Intermediate mitotic rate (>= 4 mitoses/10 HPF - for whatever ''HPF'' means, see [[HPFitis]].) | *#* A. Intermediate mitotic rate (>= 4 mitoses/10 HPF - for whatever ''HPF'' means, see [[HPFitis]].) | ||
*#*Three of the following five features: | *#* B. Three of the following five features: | ||
*#*#Sheeting architecture. | *#*#Sheeting architecture. | ||
*#*#High NC ratio clusters; clusters of "lymphocyte-like" cells. | *#*#High NC ratio clusters; clusters of "lymphocyte-like" cells. |
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