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Difference between revisions of "Myelodysplastic syndromes"
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→Dysmegakaryocytopoiesis: +IHC
(→Dysmegakaryocytopoiesis: +IHC) |
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| Line 120: | Line 120: | ||
*Non-lobated nuclei of any size. | *Non-lobated nuclei of any size. | ||
*Multiple widely separated nuclear lobes. | *Multiple widely separated nuclear lobes. | ||
=IHC= | |||
Typical [[IHC]] in work-up of MDS: | |||
*CD34 - (myeloid) progenitor/precursor cells. | |||
*CD117 - (myeloid) progenitor/precursor cells, mast cells. | |||
*Trypase - mast cells, immature basophils. | |||
**Uncommonly done. | |||
*CD61 - megakaryocytes. | |||
*CD42b - megakaryocytes. | |||
*CD20 - B cells. | |||
*CD3 - T cells. | |||
*Glycophorin A - erythroid cells. | |||
*Glycophorin C - erythroid cells. | |||
Notes: | |||
*Other megakaryocyte markers: factor VIII, vWF. (???) | |||
=See also= | =See also= | ||