Difference between revisions of "Cytogenetics"

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368 bytes added ,  15:11, 24 May 2011
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==In situ hybridization==
==In situ hybridization==
*Typically abbreviated ''ISH''.
*Typically abbreviated ''ISH''.
*Usually done with interphase nuclei.
 
===Overview===
*Usually done on interphase nuclei.
 
Comes in different flavours:
*FISH = fluorescent in situ hybridization.
*SISH = silver in situ hybridization.<ref>URL: [http://www.immunoportal.com/modules.php?name=News&file=article&sid=186 http://www.immunoportal.com/modules.php?name=News&file=article&sid=186]. Accessed on: 2 May 2011.</ref>


May be prepared from:
May be prepared from:
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===Probe types===
===Probe types===
Types:
Types:
*Fusion (two colours).
*Fusion - two colour (two different probes with different colours).
*Breakapart (two colours).
*Breakapart - two colour.
*Deletion/duplication (e.g. trisomy).
*Deletion/duplication (e.g. trisomy) - one colour.


Image:
Image:
48,830

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