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Difference between revisions of "Neuropathology tumours"
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→Oligodendroglioma: more, molecular
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===General=== | ===General=== | ||
*Arise from oligodendrocytes. | *Arise from oligodendrocytes. | ||
Usual location: | |||
*Fourth ventricle. | |||
*Intramedullary spinal cord. | |||
===Microscopic=== | ===Microscopic=== | ||
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*[http://commons.wikimedia.org/wiki/File:Oligodendroglioma1_high_mag.jpg Oligodendroglioma high mag. (WC)]. | *[http://commons.wikimedia.org/wiki/File:Oligodendroglioma1_high_mag.jpg Oligodendroglioma high mag. (WC)]. | ||
*[http://commons.wikimedia.org/wiki/File:Oligodendroglioma1_low_mag.jpg Oligodendroglioma low mag. (WC)]. | *[http://commons.wikimedia.org/wiki/File:Oligodendroglioma1_low_mag.jpg Oligodendroglioma low mag. (WC)]. | ||
===IHC=== | |||
Features: | |||
*GFAP +ve. | |||
*EMA +ve. | |||
===Molecular pathology=== | |||
Losses of 1p and 19q both helps with diagnosis and is prognostic:<ref name=pmid18565359>{{cite journal |author=Fontaine D, Vandenbos F, Lebrun C, Paquis V, Frenay M |title=[Diagnostic and prognostic values of 1p and 19q deletions in adult gliomas: critical review of the literature and implications in daily clinical practice] |language=French |journal=Rev. Neurol. (Paris) |volume=164 |issue=6-7 |pages=595–604 |year=2008 |pmid=18565359 |doi=10.1016/j.neurol.2008.04.002 |url=}}</ref> | |||
*Greater chemosensitivity | |||
*Better prognosis. | |||
==Peripheral nerve sheath tumours== | ==Peripheral nerve sheath tumours== | ||