Difference between revisions of "Chromosomal translocations"

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===EWS associated===
====EWS associated====
{| class="wikitable sortable" style="margin-left:auto;margin-right:auto"
{| class="wikitable sortable" style="margin-left:auto;margin-right:auto"
| '''Tumour'''
| '''Tumour'''
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|-
|-
|}
|}
===Lymphoma===
{| class="wikitable sortable" style="margin-left:auto;margin-right:auto"
| '''Tumour'''
| '''Translocation(s)'''
| '''Genes'''
| '''Reference(s)'''
|-
| Follicular lymphoma
| IGH-BCL2
| t(14,18)
| <ref name=pmid18684042>{{Cite journal  | last1 = Gu | first1 = K. | last2 = Chan | first2 = WC. | last3 = Hawley | first3 = RC. | title = Practical detection of t(14;18)(IgH/BCL2) in follicular lymphoma. | journal = Arch Pathol Lab Med | volume = 132 | issue = 8 | pages = 1355-61 | month = Aug | year = 2008 | doi = 10.1043/1543-2165(2008)132[1355:PDOBIF]2.0.CO;2 | PMID = 18684042 }}</ref>
|-
| Mantle cell lymphoma
| genes ???
| t(11;14)
| reference ???
|-
| Burkitt lymphoma
| genes ???
| t(8;14)
| reference ???
|-
<!-- | Tumour
| Genes
| Translocation
| Reference -->
|}
===Leukemia===
{| class="wikitable sortable" style="margin-left:auto;margin-right:auto"
| '''Tumour'''
| '''Translocation(s)'''
| '''Genes'''
| '''Reference(s)'''
|-
| Chronic myelogenous leukemia
| BCR-ABL
| t(9;22)
| <ref>{{Cite journal  | last1 = Cilloni | first1 = D. | last2 = Saglio | first2 = G. | title = CML: a model for targeted therapy. | journal = Best Pract Res Clin Haematol | volume = 22 | issue = 3 | pages = 285-94 | month = Sep | year = 2009 | doi = 10.1016/j.beha.2009.04.004 | PMID = 19959080 }}</ref>
|-
| Acute promyelocytic leukemia (APL)
| PML-RARA
| t(15;17)
| <ref name=pmid20306254>{{Cite journal  | last1 = Grimwade | first1 = D. | last2 = Mistry | first2 = AR. | last3 = Solomon | first3 = E. | last4 = Guidez | first4 = F. | title = Acute promyelocytic leukemia: a paradigm for differentiation therapy. | journal = Cancer Treat Res | volume = 145 | issue =  | pages = 219-35 | month =  | year = 2010 | doi = 10.1007/978-0-387-69259-3_13 | PMID = 20306254 }}</ref>
|-
<!-- | tumour
| genes (???)
| translocation
| reference (???) -->
|}


===Paediatric table===
===Paediatric table===
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| Tumour  
| Tumour  
| Reference -->
| Reference -->
|}
===Lymphoma===
{| class="wikitable sortable" style="margin-left:auto;margin-right:auto"
| '''Tumour'''
| '''Translocation(s)'''
| '''Genes'''
| '''Reference(s)'''
|-
| Follicular lymphoma
| genes ???
| t(14,18)
| reference ???
|-
| Mantle cell lymphoma
| genes ???
| t(11;14)
| reference ???
|-
| Burkitt lymphoma
| genes ???
| t(8;14)
| reference ???
|-
<!-- | Tumour
| Genes
| Translocation
| Reference -->
|}
===Leukemia===
{| class="wikitable sortable" style="margin-left:auto;margin-right:auto"
| '''Tumour'''
| '''Translocation(s)'''
| '''Genes'''
| '''Reference(s)'''
|-
| Chronic myelogenous leukemia
| BCR-ABL (???)
| t(9;22)
| reference (???)
|-
| Acute promyelocytic leukemia (APL)
| PML-RARA (???)
| t(15;17)
| reference (???)
|-
<!-- | tumour
| genes (???)
| translocation
| reference (???) -->
|}
|}


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