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Image: [http://www.flickr.com/photos/pulmonary_pathology/3734403695/ Wegener's granulomatosis (flickr.com)]. | Image: [http://www.flickr.com/photos/pulmonary_pathology/3734403695/ Wegener's granulomatosis (flickr.com)]. | ||
==Churg-Strauss syndrome== | |||
*AKA ''allergic granulomatous angiitis'',<ref name=emedicine333492>[http://emedicine.medscape.com/article/333492-overview http://emedicine.medscape.com/article/333492-overview]</ref>, [[AKA]] Churg-Strauss disease. | |||
===General=== | |||
Defining features - memory device ''GAFE'': | |||
*'''G'''ranulomata. | |||
*'''A'''sthma. | |||
*'''F'''ever. | |||
*'''E'''osinophilia. | |||
Notes: | |||
*Similar to ''[[Wegener's granulomatosis]]'' (classically c-ANCA +ve) and ''microscopic polyangiitis''.<ref>URL: [http://emedicine.medscape.com/article/334024-overview http://emedicine.medscape.com/article/334024-overview]. Accessed on: 22 January 2011.</ref> | |||
===Microscopic=== | |||
Features: | |||
*Small vessel [[vasculitis]]. | |||
*Abundant eosinophils. | |||
*[[Granuloma]]s. | |||
DDx: | |||
*Eosinophilic vasculitis associated with a CTD.<ref name=pmid8708015>{{Cite journal | last1 = Chen | first1 = KR. | last2 = Su | first2 = WP. | last3 = Pittelkow | first3 = MR. | last4 = Conn | first4 = DL. | last5 = George | first5 = T. | last6 = Leiferman | first6 = KM. | title = Eosinophilic vasculitis in connective tissue disease. | journal = J Am Acad Dermatol | volume = 35 | issue = 2 Pt 1 | pages = 173-82 | month = Aug | year = 1996 | doi = | PMID = 8708015 }}</ref> | |||
==LAMP-2 vasculitis== | ==LAMP-2 vasculitis== |
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