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Difference between revisions of "Thoracic SMARCA4-deficient undifferentiated tumour"
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Thoracic SMARCA4-deficient undifferentiated tumour (view source)
Revision as of 19:53, 21 August 2025
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'''Thoracic SMARCA4-deficient undifferentiated tumour''' is poorly differentiated malignancy of the thorax.<ref>{{cite journal |authors=Shinno Y, Ohe Y |title=Thoracic SMARCA4-deficient undifferentiated tumor: current knowledge and future perspectives |journal=Jpn J Clin Oncol |volume=54 |issue=3 |pages=265–270 |date=March 2024 |pmid=38117955 |doi=10.1093/jjco/hyad175 |url=}}</ref> | '''Thoracic SMARCA4-deficient undifferentiated tumour''' is poorly differentiated malignancy of the thorax.<ref name=pmid38117955>{{cite journal |authors=Shinno Y, Ohe Y |title=Thoracic SMARCA4-deficient undifferentiated tumor: current knowledge and future perspectives |journal=Jpn J Clin Oncol |volume=54 |issue=3 |pages=265–270 |date=March 2024 |pmid=38117955 |doi=10.1093/jjco/hyad175 |url=}}</ref> | ||
==General== | ==General== | ||
*It was debated whether it is carcinoma or a sarcoma.<ref>{{cite journal |authors=Rekhtman N, Montecalvo J, Chang JC, Alex D, Ptashkin RN, Ai N, Sauter JL, Kezlarian B, Jungbluth A, Desmeules P, Beras A, Bishop JA, Plodkowski AJ, Gounder MM, Schoenfeld AJ, Namakydoust A, Li BT, Rudin CM, Riely GJ, Jones DR, Ladanyi M, Travis WD |title=SMARCA4-Deficient Thoracic Sarcomatoid Tumors Represent Primarily Smoking-Related Undifferentiated Carcinomas Rather Than Primary Thoracic Sarcomas |journal=J Thorac Oncol |volume=15 |issue=2 |pages=231–247 |date=February 2020 |pmid=31751681 |pmc=7556987 |doi=10.1016/j.jtho.2019.10.023 |url=}}</ref> | *It was debated whether it is a poorly differentiated [[carcinoma]] or a [[sarcoma]].<ref name=pmid31751681>{{cite journal |authors=Rekhtman N, Montecalvo J, Chang JC, Alex D, Ptashkin RN, Ai N, Sauter JL, Kezlarian B, Jungbluth A, Desmeules P, Beras A, Bishop JA, Plodkowski AJ, Gounder MM, Schoenfeld AJ, Namakydoust A, Li BT, Rudin CM, Riely GJ, Jones DR, Ladanyi M, Travis WD |title=SMARCA4-Deficient Thoracic Sarcomatoid Tumors Represent Primarily Smoking-Related Undifferentiated Carcinomas Rather Than Primary Thoracic Sarcomas |journal=J Thorac Oncol |volume=15 |issue=2 |pages=231–247 |date=February 2020 |pmid=31751681 |pmc=7556987 |doi=10.1016/j.jtho.2019.10.023 |url=}}</ref> | ||
*WHO recognized entity as of 2021.<ref name=pmid38306886>{{cite journal |vauthors=Zhou P, Fu Y, Tang Y, Jiang L, Wang W |title=Thoracic SMARCA4-deficient undifferentiated tumor: A clinicopathological and prognostic analysis of 35 cases and immunotherapy efficacy |journal=Lung Cancer |volume=189 |issue= |pages=107471 |date=March 2024 |pmid=38306886 |doi=10.1016/j.lungcan.2024.107471 |url=}}</ref> | |||
==Microscopic== | ==Microscopic== | ||