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Difference between revisions of "Thoracic SMARCA4-deficient undifferentiated tumour"
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Thoracic SMARCA4-deficient undifferentiated tumour (view source)
Revision as of 19:46, 21 August 2025
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'''Thoracic SMARCA4-deficient undifferentiated tumour''' is poorly differentiated malignancy of the thorax.<ref>{{cite journal |authors=Shinno Y, Ohe Y |title=Thoracic SMARCA4-deficient undifferentiated tumor: current knowledge and future perspectives |journal=Jpn J Clin Oncol |volume=54 |issue=3 |pages=265–270 |date=March 2024 |pmid=38117955 |doi=10.1093/jjco/hyad175 |url=}}</ref> | '''Thoracic SMARCA4-deficient undifferentiated tumour''' is poorly differentiated malignancy of the thorax.<ref>{{cite journal |authors=Shinno Y, Ohe Y |title=Thoracic SMARCA4-deficient undifferentiated tumor: current knowledge and future perspectives |journal=Jpn J Clin Oncol |volume=54 |issue=3 |pages=265–270 |date=March 2024 |pmid=38117955 |doi=10.1093/jjco/hyad175 |url=}}</ref> | ||
==Microscopic== | |||
Features: | |||
*Poorly differentiated malignancy. | |||
*+/-[[Rhabdoid morphology]]. | |||
==IHC== | |||
*SMARCA4 loss or strongly reduced (definitional). | |||
*AE1/AE3 -ve or focal. | |||
*Synaptophysin +ve. | |||
*Chromogranin -ve. | |||
==See also== | |||
*[[SMARCA4]]. | |||
==References== | ==References== | ||