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'''Lymphovascular invasion''', also '''lymphovascular space invasion''', is (non-hematologic) malignant cells within [[blood vessels]] and/or lymphatics. It is abbreviated '''LVI'''. | '''Lymphovascular invasion''', also '''lymphovascular space invasion''', is (non-hematologic) malignant cells within [[blood vessels]] and/or lymphatics. It is abbreviated '''LVI'''. | ||
In some contexts, ''[[vascular invasion]]'' (also ''angioinvasion'') must be separated from ''lymphovascular invasion''.<ref>{{cite journal |authors=Mete O, Erickson LA, Juhlin CC, de Krijger RR, Sasano H, Volante M, Papotti MG |title=Overview of the 2022 WHO Classification of Adrenal Cortical Tumors |journal=Endocr Pathol |volume=33 |issue=1 |pages=155–196 |date=March 2022 |pmid=35288842 |pmc=8920443 |doi=10.1007/s12022-022-09710-8 |url=}}</ref> | |||
The term ''lymphovascular invasion'' was traditionally preferred to ''[[vascular invasion]]'', as it is difficult to differentiate morphologically small lymphatics and small vascular spaces, without [[immunohistochemistry]]. | |||
==General== | ==General== | ||
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