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Difference between revisions of "Adrenal cortical adenoma"
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| Line 7: | Line 7: | ||
| Micro = | | Micro = | ||
| Subtypes = | | Subtypes = | ||
| LMDDx = adrenal cortical nodule, | | LMDDx = adrenal cortical nodule, adrenal cortical hyperplasia, [[adrenal cortical carcinoma]] | ||
| Stains = | | Stains = | ||
| IHC = [[calretinin]], inhibin | | IHC = [[calretinin]], inhibin | ||
| EM = | | EM = | ||
| Molecular = | | Molecular = cortisol-producing (PRKACA, GNAS1, MENIN, ARMC5, APC, FH, PRKAR1A, PDE11A, PDE8B), aldosterone-producing | ||
(KCNJ5, ATP1A1, ATP2B3, CACNA1D, CTNNB1), non-secreting (CTNNB1) | |||
| IF = | | IF = | ||
| Gross = | | Gross = | ||
| Line 20: | Line 21: | ||
| Clinicalhx = | | Clinicalhx = | ||
| Signs = | | Signs = | ||
| Symptoms = | | Symptoms = | ||
| Prevalence = relatively common | | Prevalence = relatively common | ||
| Bloodwork = | | Bloodwork = +/-cortisol elevation, +/-aldosterone elevation | ||
| Rads = adrenal mass, HU<10 | | Rads = adrenal mass, HU<10 | ||
| Endoscopy = | | Endoscopy = | ||