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Difference between revisions of "TFE3-rearranged renal cell carcinoma"
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| LMDDx = [[clear cell renal cell carcinoma]], [[papillary renal cell carcinoma]], [[epithelioid angiomyolipoma]], [[clear cell papillary renal cell carcinoma]], [[unclassified renal cell carcinoma]], [[melanotic Xp11 translocation renal cancer]] (evolving entity) | | LMDDx = [[clear cell renal cell carcinoma]], [[papillary renal cell carcinoma]], [[epithelioid angiomyolipoma]], [[clear cell papillary renal cell carcinoma]], [[unclassified renal cell carcinoma]], [[melanotic Xp11 translocation renal cancer]] (evolving entity) | ||
| Stains = | | Stains = | ||
| IHC = TFE3 +ve (nucleus), CD10 +ve, vimentin +ve, CK7 -ve (usu.) | | IHC = TFE3 +ve (nucleus), CD10 +ve, vimentin +ve, CK7 -ve (usu.), cathepsin K +ve, EMA -ve, AE1/AE3 +ve (usu. focal) | ||
| EM = | | EM = | ||
| Molecular = [[translocation]] involving TFE3, e.g. t(X;1)(p11.2;q21) | | Molecular = [[translocation]] involving TFE3, e.g. t(X;1)(p11.2;q21) | ||