Difference between revisions of "Clear cell renal cell carcinoma"

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| Micro      = solid or [[trabecular]] pattern, polygonal cells usually with clear cytoplasm (may be eosinophilic - esp. in high grade tumours), central nucleus, delicate branching vasculature (chicken wire-like), +/-hyaline bodies
| Micro      = solid or [[trabecular]] pattern, polygonal cells usually with clear cytoplasm (may be eosinophilic - esp. in high grade tumours), central nucleus, delicate branching vasculature (chicken wire-like), +/-hyaline bodies
| Subtypes  =  
| Subtypes  =  
| LMDDx      = [[chromophobe renal cell carcinoma]], [[clear cell papillary renal cell tumour]], [[Xp11.2 translocation carcinoma]], [[ELOC-mutated renal cell carcinoma]], [[renal cell carcinoma with fibromyomatous stroma]], [[benign clear cell clusters of the kidney]], [[alveolar soft part sarcoma]], [[adrenocortical carcinoma]]
| LMDDx      = [[chromophobe renal cell carcinoma]], [[clear cell papillary renal cell tumour]], [[Xp11.2 translocation carcinoma]], [[ELOC-mutated renal cell carcinoma]], [[renal cell carcinoma with fibromyomatous stroma]], [[benign clear cell clusters of the kidney]], [[alveolar soft part sarcoma]], [[adrenocortical carcinoma]], [[hemangioblastoma of the kidney]]
| Stains    = PAS +ve, PAS-D -ve, [[Hale's colloidal iron stain]] -ve
| Stains    = PAS +ve, PAS-D -ve, [[Hale's colloidal iron stain]] -ve
| IHC        = [[CA9]] +ve, CK7 -ve, CK20 -ve, TFE3 -ve, PAX8 +ve, vimentin +ve
| IHC        = [[CA9]] +ve, CK7 -ve, CK20 -ve, TFE3 -ve, PAX8 +ve, vimentin +ve
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*[[Benign clear cell clusters of the kidney]].  
*[[Benign clear cell clusters of the kidney]].  
*[[Renal cell carcinoma with fibromyomatous stroma]].
*[[Renal cell carcinoma with fibromyomatous stroma]].
*[[Hemangioblastoma of the kidney]] - especially in [[Von Hippel-Lindau disease]].
**S-100 +ve, inhibin +ve, PAX-8+ve, EMA -ve, CA9 -ve.


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