48,976
edits
Difference between revisions of "Clear cell renal cell carcinoma"
Jump to navigation
Jump to search
no edit summary
| Line 7: | Line 7: | ||
| Micro = solid or [[trabecular]] pattern, polygonal cells usually with clear cytoplasm (may be eosinophilic - esp. in high grade tumours), central nucleus, delicate branching vasculature (chicken wire-like), +/-hyaline bodies | | Micro = solid or [[trabecular]] pattern, polygonal cells usually with clear cytoplasm (may be eosinophilic - esp. in high grade tumours), central nucleus, delicate branching vasculature (chicken wire-like), +/-hyaline bodies | ||
| Subtypes = | | Subtypes = | ||
| LMDDx = [[chromophobe renal cell carcinoma]], [[clear cell papillary renal cell tumour]], [[Xp11.2 translocation carcinoma]], [[ELOC-mutated renal cell carcinoma]], [[renal cell carcinoma with fibromyomatous stroma]], [[benign clear cell clusters of the kidney]], [[alveolar soft part sarcoma]], [[adrenocortical carcinoma]] | | LMDDx = [[chromophobe renal cell carcinoma]], [[clear cell papillary renal cell tumour]], [[Xp11.2 translocation carcinoma]], [[ELOC-mutated renal cell carcinoma]], [[renal cell carcinoma with fibromyomatous stroma]], [[benign clear cell clusters of the kidney]], [[alveolar soft part sarcoma]], [[adrenocortical carcinoma]], [[hemangioblastoma of the kidney]] | ||
| Stains = PAS +ve, PAS-D -ve, [[Hale's colloidal iron stain]] -ve | | Stains = PAS +ve, PAS-D -ve, [[Hale's colloidal iron stain]] -ve | ||
| IHC = [[CA9]] +ve, CK7 -ve, CK20 -ve, TFE3 -ve, PAX8 +ve, vimentin +ve | | IHC = [[CA9]] +ve, CK7 -ve, CK20 -ve, TFE3 -ve, PAX8 +ve, vimentin +ve | ||
| Line 102: | Line 102: | ||
*[[Benign clear cell clusters of the kidney]]. | *[[Benign clear cell clusters of the kidney]]. | ||
*[[Renal cell carcinoma with fibromyomatous stroma]]. | *[[Renal cell carcinoma with fibromyomatous stroma]]. | ||
*[[Hemangioblastoma of the kidney]] - especially in [[Von Hippel-Lindau disease]]. | |||
**S-100 +ve, inhibin +ve, PAX-8+ve, EMA -ve, CA9 -ve. | |||
===Images=== | ===Images=== | ||