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==General== | ==General== | ||
*PRAME is an acronym for ''PReferentially expressed Antigen in MElanoma''. | |||
==Positive staining== | ==Positive staining== | ||
*80-85% of primary melanomas.<ref name=pmid30045064/> | *80-85% of primary melanomas.<ref name=pmid30045064/> | ||
*85-90% of metastatic melanomas.<ref name=pmid30045064/> | *85-90% of metastatic melanomas.<ref name=pmid30045064/> | ||
Pattern:<ref>{{cite journal |authors=Lezcano C, Jungbluth AA, Busam KJ |title=PRAME Immunohistochemistry as an Ancillary Test for the Assessment of Melanocytic Lesions |journal=Surg Pathol Clin |volume=14 |issue=2 |pages=165–175 |date=June 2021 |pmid=34023098 |pmc=8152939 |doi=10.1016/j.path.2021.01.001 |url=}}</ref> | |||
*Nuclear staining. | |||
==See also== | ==See also== | ||
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