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Difference between revisions of "Small cell carcinoma of the lung"
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Small cell carcinoma of the lung (view source)
Revision as of 22:35, 16 January 2025
, 22:35, 16 January 2025no edit summary
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==Molecular== | |||
Four molecular subtypes - defined by the key transcriptional regulators:<ref>{{cite journal |authors=Rudin CM, Poirier JT, Byers LA, Dive C, Dowlati A, George J, Heymach JV, Johnson JE, Lehman JM, MacPherson D, Massion PP, Minna JD, Oliver TG, Quaranta V, Sage J, Thomas RK, Vakoc CR, Gazdar AF |title=Molecular subtypes of small cell lung cancer: a synthesis of human and mouse model data |journal=Nat Rev Cancer |volume=19 |issue=5 |pages=289–297 |date=May 2019 |pmid=30926931 |pmc=6538259 |doi=10.1038/s41568-019-0133-9 |url=}}</ref> | |||
*ASCL1 = achaete-scute homologue 1. | |||
*NeuroD1 = neurogenic differentiation factor 1. | |||
*YAP1 = yes-associated protein 1. | |||
*POU2F3 = POU class 2 homeobox 3. | |||
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