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Difference between revisions of "Cholangiocarcinoma"
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+more SO
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(+more SO) |
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Note: | Note: | ||
*On biopsy, it isn't possible to cleanly separate from [[pancreatic adenocarcinoma]]. Thus, it is better to stay vague. | *On biopsy, it isn't possible to cleanly separate from [[pancreatic adenocarcinoma]]. Thus, it is better to stay vague. | ||
===Alternate=== | |||
<pre> | |||
Liver, Core Biopsy: | |||
- ADENOCARCINOMA, see comment. | |||
Comment: | |||
The tumour stains as follows: | |||
POSITIVE: CK7 (strong, diffuse), CK19 (moderate, diffuse), HNF1b (moderate, diffuse). | |||
NEGATIVE: CK20, GATA3, HepPar-1, PAX-8, WT-1, CDX2, mammaglobin, TTF-1. | |||
The findings would be compatible with a foregut primary lesion; a non-exhaustive list of possibilities includes: cholangiocarcinoma, pancreatic adenocarcinoma and gastric adenocarcinoma. Clinical and radiologic correlation is required. | |||
</pre> | |||
===Micro=== | ===Micro=== | ||
The sections show an atypical gland-forming lesion (adenocarcinoma) in a fibrous | The sections show an atypical gland-forming lesion (adenocarcinoma) in a fibrous | ||