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Difference between revisions of "Residual cancer burden index"
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The [[RCB index]] is defined as:<ref name=pmid17785706>{{cite journal |authors=Symmans WF, Peintinger F, Hatzis C, Rajan R, Kuerer H, Valero V, Assad L, Poniecka A, Hennessy B, Green M, Buzdar AU, Singletary SE, Hortobagyi GN, Pusztai L |title=Measurement of residual breast cancer burden to predict survival after neoadjuvant chemotherapy |journal=J Clin Oncol |volume=25 |issue=28 |pages=4414–22 |date=October 2007 |pmid=17785706 |doi=10.1200/JCO.2007.10.6823 |url=}}</ref> | The [[RCB index]] is defined as:<ref name=pmid17785706>{{cite journal |authors=Symmans WF, Peintinger F, Hatzis C, Rajan R, Kuerer H, Valero V, Assad L, Poniecka A, Hennessy B, Green M, Buzdar AU, Singletary SE, Hortobagyi GN, Pusztai L |title=Measurement of residual breast cancer burden to predict survival after neoadjuvant chemotherapy |journal=J Clin Oncol |volume=25 |issue=28 |pages=4414–22 |date=October 2007 |pmid=17785706 |doi=10.1200/JCO.2007.10.6823 |url=}}</ref> | ||
:<math>RCB = 1.4 \ ( f_{inv} \ d_{prim} )^ {0.17} + \lbrack{ \ 4 \ (1 - 0.75^{LN}) d_{met}} \rbrack ^{0.17}</math> | :<math>RCB = 1.4 \ ( f_{inv} \ d_{prim} )^ {0.17} + \lbrack{ \ 4 \ (1 - 0.75^{LN}) d_{met}} \rbrack ^{0.17}</math> | ||
Where: | |||
:<math>f_{inv} = \text {portion of tumour bed that is viable invasive tumour}</math> | |||
:<math>d_{prim} = \sqrt {d_1 \ d_2}</math> | |||
:<math>\text{LN} = \text {number of lymph nodes with metastatic carcinoma}</math> | |||
:<math>d_{met} = \text {diameter of the largest lymph node metastasis}</math> | |||
The inputs to <math>d_{prim}</math> are: | |||
:<math>d_1 = \text{first in-plane tumour dimension}</math> | |||
:<math>d_1 = \text{second in-plane tumour dimension}</math> | |||
==See also== | ==See also== | ||