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Difference between revisions of "Eccrine spiradenoma"
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'''Eccrine spiradenoma''' is a benign skin thingy. | '''Eccrine spiradenoma''', also '''spiradenoma''',<ref>URL: [http://emedicine.medscape.com/article/1062079-overview http://emedicine.medscape.com/article/1062079-overview]. Accessed on: 9 May 2011.</ref> is a benign skin thingy. There is case series of malignant ones.<ref name=pmid20851376>{{Cite journal | last1 = Andreoli | first1 = MT. | last2 = Itani | first2 = KM. | title = Malignant eccrine spiradenoma: a meta-analysis of reported cases. | journal = Am J Surg | volume = 201 | issue = 5 | pages = 688-92 | month = May | year = 2011 | doi = 10.1016/j.amjsurg.2010.04.015 | PMID = 20851376 }}</ref> | ||
==General== | ==General== | ||
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*Apocrine differentiation, i.e. apocrine snouts. | *Apocrine differentiation, i.e. apocrine snouts. | ||
Images: | |||
*[http://commons.wikimedia.org/wiki/File:Eccrine_spiradenoma_-_very_low_mag.jpg Eccrine spiradenoma - very low mag. (WC)]. | |||
*[http://commons.wikimedia.org/wiki/File:Eccrine_spiradenoma_-_very_high_mag.jpg Eccrine spiradenoma - very high mag. (WC)]. | |||
*[http://dermimages.med.jhmi.edu/images/spiradenoma_2_060109.jpg Eccrine spiradenoma (dermimages.med.jhmi.edu)].<ref name=dermatlas>URL: [http://www.dermatlas.com/derm/IndexDisplay.cfm?ImageID=-1193575448 http://www.dermatlas.com/derm/IndexDisplay.cfm?ImageID=-1193575448]. Accessed on: 29 November 2010.</ref> | |||
==IHC== | |||
Features:<ref name=pmid9129700>{{Cite journal | last1 = Meybehm | first1 = M. | last2 = Fischer | first2 = HP. | title = Spiradenoma and dermal cylindroma: comparative immunohistochemical analysis and histogenetic considerations. | journal = Am J Dermatopathol | volume = 19 | issue = 2 | pages = 154-61 | month = Apr | year = 1997 | doi = | PMID = 9129700 }}</ref> | |||
*S100 +ve. | |||
*Keratins 7, 8, and 18 +ve. | |||
Notes: | |||
*IHC profile essentially identical to dermal cylindroma.<ref name=pmid9129700/> | |||
==See also== | ==See also== | ||
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==References== | ==References== | ||
{{Reflist| | {{Reflist|2}} | ||
[[Category:Dermatopathology]] | [[Category:Dermatopathology]] | ||