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(→IHC) |
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Line 72: | Line 72: | ||
*CK20 -ve. | *CK20 -ve. | ||
*CD10 -ve. | *CD10 -ve. | ||
==Sign out== | |||
<pre> | |||
Right Kidney Mass, Biopsy: | |||
- Low-grade oncocytic tumour (see comment). | |||
Comment: | |||
The tumour stains as follows: | |||
POSITIVE: CK7 (strong, diffuse), CD117 (very focal), PAX8 (strong, diffuse), AE1/AE3, AMACR, E-cadherin, BerEP4. | |||
NEGATIVE: CD10, CK20, vimentin, CA9. | |||
This tumour does not completely fit the diagnosis of renal oncocytoma or eosinophilic chromophobe renal cell carcinoma. | |||
It is in keeping with "low-grade oncocytic tumour" (LOT), an evolving entity. Based on limited data, LOT appears to have an indolent behavior. | |||
</pre> | |||
==See also== | ==See also== |
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