Difference between revisions of "ELOC-mutated renal cell carcinoma"

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ELOC-mutated renal cell carcinoma (view source)

Revision as of 21:56, 11 October 2022

18 bytes removed ,  21:56, 11 October 2022
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Right Kidney, Radical Nephrectomy:  
Right Kidney, Radical Nephrectomy:  
     - CLEAR CELL RENAL CELL CARCINOMA with cysts and leiomyomatous  
     - RENAL CELL CARCINOMA with clear cells, cysts and leiomyomatous stroma, see comment.
        stroma, see comment.
     -- Margin clear.
     -- Margin clear.
     -- Please see synoptic report for details.
     -- Please see synoptic report for details.
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NEGATIVE: CK34betaE12, CK20.
NEGATIVE: CK34betaE12, CK20.


The staining and morphology raises the possibility of a TCEB1 mutation, described
The staining and morphology raises the possibility of a ELOC-mutated renal cell carcinoma (RCC).
in a subset of clear cell renal cell carcinoma.[1]


1. Mod Pathol 28 (6): 845-53. doi:10.1038/modpathol.2015.6. PMID 25676555.
The differential diagnosis includes: (1) RCC with a mTOR pathway mutation, and (2) ELOC-mutated RCC.
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Michael
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