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'''Peritoneal inclusion cyst''' is a relatively uncommon benign pathology of the peritoneum.<ref name=pmid19386139>{{Cite journal | last1 = Vallerie | first1 = AM. | last2 = Lerner | first2 = JP. | last3 = Wright | first3 = JD. | last4 = Baxi | first4 = LV. | title = Peritoneal inclusion cysts: a review. | journal = Obstet Gynecol Surv | volume = 64 | issue = 5 | pages = 321-34 | month = May | year = 2009 | doi = 10.1097/OGX.0b013e31819f93d4 | PMID = 19386139 }}</ref> | |||
It is also known as '''benign multicystic mesothelioma'''; it should '''not''' be confused with ''[[malignant mesothelioma]]'' and ''[[benign papillary mesothelioma]]''. | |||
It may referred to as '''inflammatory cyst of the peritoneum''', '''[[mesothelial inclusion cyst]]'''.{{fact}} | |||
'''Multilocular peritoneal inclusion cyst''' redirect here. | |||
===General=== | |||
*Usually conservative management. | |||
*Serum CA-125 usually low. | |||
*May occur in men.<ref name=pmid12239771>{{Cite journal | last1 = Cavallaro | first1 = A. | last2 = Murazio | first2 = M. | last3 = Modugno | first3 = P. | last4 = Vona | first4 = A. | last5 = Revelli | first5 = L. | last6 = Potenza | first6 = AE. | last7 = Colli | first7 = R. | title = Benign multicystic mesothelioma of the peritoneum: a case report. | journal = Chir Ital | volume = 54 | issue = 4 | pages = 569-72 | month = | year = | doi = | PMID = 12239771 }}</ref> | |||
===Gross=== | |||
Features:<ref name=pmid3789251>{{Cite journal | last1 = McFadden | first1 = DE. | last2 = Clement | first2 = PB. | title = Peritoneal inclusion cysts with mural mesothelial proliferation. A clinicopathological analysis of six cases. | journal = Am J Surg Pathol | volume = 10 | issue = 12 | pages = 844-54 | month = Dec | year = 1986 | doi = | PMID = 3789251 }}</ref> | |||
*Multilocular thin-walled cysts containing serous fluid +/- blood. | |||
**Occasionally unilocular. | |||
*May be up to 15 cm. | |||
*Can be adherent to the [[ovary]]. | |||
===Microscopic=== | |||
Features:<ref name=pmid19386139/><ref name=pmid18349460>{{Cite journal | last1 = Levy | first1 = AD. | last2 = Arnáiz | first2 = J. | last3 = Shaw | first3 = JC. | last4 = Sobin | first4 = LH. | title = From the archives of the AFIP: primary peritoneal tumors: imaging features with pathologic correlation. | journal = Radiographics | volume = 28 | issue = 2 | pages = 583-607; quiz 621-2 | month = | year = | doi = 10.1148/rg.282075175 | PMID = 18349460 | URL = http://radiographics.rsna.org/content/28/2/583.full}}</ref> | |||
*Thin-walled, irregular-shaped, cysts - unicystic or multicystic. | |||
**Mesothelial lining +/- squamous metaplasia.<ref name=pmid2766227>{{Cite journal | last1 = Ross | first1 = MJ. | last2 = Welch | first2 = WR. | last3 = Scully | first3 = RE. | title = Multilocular peritoneal inclusion cysts (so-called cystic mesotheliomas). | journal = Cancer | volume = 64 | issue = 6 | pages = 1336-46 | month = Sep | year = 1989 | doi = | PMID = 2766227 }} | |||
</ref> | |||
**Eosinophilic fluid. | |||
DDx: | |||
*[[Ovarian serous borderline tumour]]. | |||
*[[Ovarian serous carcinoma]]. | |||
*[[Primary peritoneal serous carcinoma]]. | |||
*Primary peritoneal [[malignant mesothelioma]]. | |||
Images: | |||
*[http://radiographics.rsna.org/content/28/2/583/F30.expansion.html Multicystic mesothelioma (rsna.org)]. | |||
*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3445851/figure/F4/ Benign multicystic peritoneal mesothelioma (nih.gov)].<ref name=pmid22583977>{{Cite journal | last1 = Takemoto | first1 = S. | last2 = Kawano | first2 = R. | last3 = Honda | first3 = K. | last4 = Nakazono | first4 = A. | last5 = Shimamatsu | first5 = K. | title = Benign multicystic peritoneal mesothelioma mimicking recurrence of an ovarian borderline tumor: a case report. | journal = J Med Case Rep | volume = 6 | issue = 1 | pages = 126 | month = | year = 2012 | doi = 10.1186/1752-1947-6-126 | PMID = 22583977 }}</ref> | |||
===IHC=== | |||
Features:<ref name=pmid22583977/> | |||
*Calretinin +ve. | |||
*WT-1 +ve. | |||
==See also== | |||
*[[Peritoneum]]. | |||
==References== | |||
{{Reflist|1}} | |||
[[Category:Gynecologic pathology]] |
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