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→IHC: Update
Jensflorian (talk | contribs) (Cleaning up) |
Jensflorian (talk | contribs) (→IHC: Update) |
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===IHC=== | ===By IHC=== | ||
*GFAP - should stain cytoplasm of tumour cells and the perikaryon (nuclear membrane) | *GFAP - should stain cytoplasm of tumour cells and the perikaryon (nuclear membrane) of most [[Astrocytoma]]s. | ||
*[[IDH-1]](R132H) (isocitrate dehydrogenase 1) in [[Astrocytoma, IDH-mutant]].<ref name=pmid19228619>{{cite journal |author=Yan H, Parsons DW, Jin G, ''et al.'' |title=IDH1 and IDH2 mutations in gliomas |journal=N. Engl. J. Med. |volume=360 |issue=8 |pages=765–73 |year=2009 |month=February |pmid=19228619 |pmc=2820383 |doi=10.1056/NEJMoa0808710 |url=}}</ref><ref name=pmid20975057>{{cite journal |author=Houillier C, Wang X, Kaloshi G, ''et al.'' |title=IDH1 or IDH2 mutations predict longer survival and response to temozolomide in low-grade gliomas |journal=Neurology |volume=75 |issue=17 |pages=1560–6 |year=2010 |month=October |pmid=20975057 |doi=10.1212/WNL.0b013e3181f96282 |url=}}</ref> | |||
*[[H3F3A|H3F3A K27M]] in [[Diffuse midline glioma, H3 K27-altered]]. | |||
*[[IDH-1]] (isocitrate dehydrogenase 1) | *[[ATRX]] -ve in [[Astrocytoma, IDH-mutant]] or [[Diffuse hemispheric glioma, H3 G34-mutant]]. | ||
*[[CD20]] in PCNSL. | |||
*Cytokeratins in Carcinoma brain metastases, Plexus choroid tumours, [[AT/RT]], [[Papillary tumour of the pineal region]], [[Craniopharyngioma]]. | |||
===Common neuropathology tumours in a table=== | ===Common neuropathology tumours in a table=== | ||