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Difference between revisions of "Neuropathology tumours"
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→Common neuropathology tumours in a table: Arabic numerals in WHO grades
Jensflorian (talk | contribs) (→Gliomas: Update) |
Jensflorian (talk | contribs) (→Common neuropathology tumours in a table: Arabic numerals in WHO grades) |
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|[[Image:Meningioma_intermed_mag.jpg |thumb|center|150px|Meningioma. (WC)]] | |[[Image:Meningioma_intermed_mag.jpg |thumb|center|150px|Meningioma. (WC)]] | ||
|- | |- | ||
| | |[[Astrocytoma, IDH-mutant]] (CNS [[WHO]] grade 2 or grade 3) | ||
|glial processes (esp. on smear), nuclear atypia (typical size var. ~3x, irreg. nuc. membrane, hyperchromasia), no Rosenthal fibres in the core of the lesion †, no microvascular proliferation, no necrosis | |glial processes (esp. on smear), nuclear atypia (typical size var. ~3x, irreg. nuc. membrane, hyperchromasia), no Rosenthal fibres in the core of the lesion †, no microvascular proliferation, no necrosis | ||
|often enhancing (suggests high grade), usu. supratentorial, usu. white matter | |often enhancing (suggests high grade), usu. supratentorial, usu. white matter | ||
|usu. old, occ. young | |usu. old, occ. young | ||
|common | |common | ||
|IDH-1+/-, GFAP+ | |IDH-1(R132H)+/-, GFAP+ | ||
| [[Image:Anaplastic_astrocytoma_-_very_high_mag_-_cropped.jpg | thumb| center| 150px|High-grade astrocytoma. (WC)]] | | [[Image:Anaplastic_astrocytoma_-_very_high_mag_-_cropped.jpg | thumb| center| 150px|High-grade astrocytoma. (WC)]] | ||
|- | |- | ||
|[[Glioblastoma]] (WHO grade | |[[Glioblastoma]], IDH-wildtype (CNS [[WHO]] grade 4) | ||
|glial processes (esp. on smear), nuclear atypia (typical size var. ~3x, irreg. nuc. membrane, hyperchromasia), no Rosenthal fibres in the core of the lesion †, microvascular proliferation or necrosis | |glial processes (esp. on smear), nuclear atypia (typical size var. ~3x, irreg. nuc. membrane, hyperchromasia), no Rosenthal fibres in the core of the lesion †, microvascular proliferation or necrosis | ||
|often enhancing (suggests high grade), usu. supratentorial, usu. white matter | |often enhancing (suggests high grade), usu. supratentorial, usu. white matter | ||