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→Classic ependymoma: DDx
Jensflorian (talk | contribs) (→Molecular: update) |
Jensflorian (talk | contribs) (→Classic ependymoma: DDx) |
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==Microscopic== | ==Microscopic== | ||
===Classic ependymoma=== | ==="Classic" ependymoma=== | ||
*Come in two CNS WHO grades: 2 and 3. | *Come in two CNS WHO grades: 2 and 3. | ||
*Usu. sharply demarcated from surrounding brain parenchyma. | *Usu. sharply demarcated from surrounding brain parenchyma. | ||
| Line 94: | Line 94: | ||
*Branching capillaries usu. only in supratentorial ependymomas. | *Branching capillaries usu. only in supratentorial ependymomas. | ||
DDx ( | DDx (supratentorial and posterior fossa ependymoma): | ||
*[[Subependymoma]]. | *[[Subependymoma]]. | ||
*[[Glioblastoma]] (GBM). | *[[Glioblastoma]] (GBM). | ||
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*[[Astroblastoma]], MN1-altered. | *[[Astroblastoma]], MN1-altered. | ||
**Invasive border = GBM; circumscribed border of lesion = ependymoma. | **Invasive border = GBM; circumscribed border of lesion = ependymoma. | ||
*[[Oligodendroglioma]] (Clear cell ependymoma)) | |||
DDx (spinal ependymoma): | |||
*[[Pilocytic astrocytoma]] (Tanycytic ependymoma) | *[[Pilocytic astrocytoma]] (Tanycytic ependymoma) | ||
* | *Diffuse midline glioma, H3 K27-altered | ||
*Small cell glioblastoma (MYCN-amplified spinal ependymoma) | |||
====Images==== | ====Images==== | ||