Difference between revisions of "Classification of urothelial carcinoma by immunohistochemistry"

Jump to navigation Jump to search
no edit summary
Line 20: Line 20:
*p16.
*p16.


Note:
Notes:
*Twenty percent of the tumour cells is considered the cut-off for ''positive'' and ''negative''.<ref name=pmid34103388/>
*Twenty percent of the tumour cells is considered the cut-off for ''positive'' and ''negative''.<ref name=pmid34103388/>
*GATA3 ''positive'' and CK5/6 ''positive'' cases are classified as ''luminal''.<ref name=pmid34103388/>
*GATA3 ''negative'' and CK5/6 ''negative'' are ''unclassified''.<ref name=pmid34103388/>


==Sign out==
==Sign out==
Line 35: Line 38:
The immunoprofile (CK5/6 POSITIVE, GATA3 negative) is in keeping with UROTHELIAL CARCINOMA, BASAL TYPE.
The immunoprofile (CK5/6 POSITIVE, GATA3 negative) is in keeping with UROTHELIAL CARCINOMA, BASAL TYPE.
</pre>
</pre>
===Notes===
*A marker is considered POSITIVE when 20% of tumour cells are POSITIVE.<ref name=pmid34103388/>
*GATA3 POSITIVE and CK5/6 POSITIVE cases are classified as ''luminal''.<ref name=pmid34103388/>
*GATA3 NEGATIVE and CK5/6 NEGATIVE are ''unclassified''.<ref name=pmid34103388/>


==See also==
==See also==
48,830

edits

Navigation menu