Difference between revisions of "Classification of urothelial carcinoma by immunohistochemistry"

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*p16.
*p16.


Note:
Notes:
*Twenty percent of the tumour cells is considered the cut-off for ''positive'' and ''negative''.<ref name=pmid34103388/>
*Twenty percent of the tumour cells is considered the cut-off for ''positive'' and ''negative''.<ref name=pmid34103388/>
*GATA3 ''positive'' and CK5/6 ''positive'' cases are classified as ''luminal''.<ref name=pmid34103388/>
*GATA3 ''negative'' and CK5/6 ''negative'' are ''unclassified''.<ref name=pmid34103388/>


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The immunoprofile (CK5/6 POSITIVE, GATA3 negative) is in keeping with UROTHELIAL CARCINOMA, BASAL TYPE.
The immunoprofile (CK5/6 POSITIVE, GATA3 negative) is in keeping with UROTHELIAL CARCINOMA, BASAL TYPE.
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===Notes===
*A marker is considered POSITIVE when 20% of tumour cells are POSITIVE.<ref name=pmid34103388/>
*GATA3 POSITIVE and CK5/6 POSITIVE cases are classified as ''luminal''.<ref name=pmid34103388/>
*GATA3 NEGATIVE and CK5/6 NEGATIVE are ''unclassified''.<ref name=pmid34103388/>


==See also==
==See also==
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