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Difference between revisions of "Sinonasal undifferentiated carcinoma"
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Sinonasal undifferentiated carcinoma (view source)
Revision as of 14:22, 4 October 2021
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*SMARCB1 ([[INI1]]) +ve (nuclear staining present). | *SMARCB1 ([[INI1]]) +ve (nuclear staining present). | ||
**Nuclear staining lost in [[SMARCB1-deficient sinonasal carcinoma]]. | **Nuclear staining lost in [[SMARCB1-deficient sinonasal carcinoma]]. | ||
===Comparison between different H&N carcinomas=== | |||
Keratins can subclassify the H&N carcinomas:<reF>{{cite journal |vauthors=Franchi A, Moroni M, Massi D, Paglierani M, Santucci M |title=Sinonasal undifferentiated carcinoma, nasopharyngeal-type undifferentiated carcinoma, and keratinizing and nonkeratinizing squamous cell carcinoma express different cytokeratin patterns |journal=Am J Surg Pathol |volume=26 |issue=12 |pages=1597–604 |date=December 2002 |pmid=12459626 |doi=10.1097/00000478-200212000-00007 |url=}}</ref> | |||
{| class="wikitable sortable" | |||
! Diagnosis | |||
! CK4 | |||
! CK5/6 | |||
! CK7 | |||
! CK13 | |||
! CK14 | |||
! CK19 | |||
|- | |||
| Sinonasal undifferentiated carcinoma (SNUC) | |||
| 0% | |||
| 0% | |||
| 50% | |||
| 0% | |||
| 0% | |||
| 50% | |||
|- | |||
| Nasopharyngeal-type undifferentiated carcinoma (NPTC) | |||
| 0% | |||
| 80% | |||
| 0% | |||
| 80% | |||
| 0% | |||
| 100% | |||
|- | |||
| Nonkeratinizing squamous cell carcinoma (NKSCC) | |||
| 0% | |||
| 90% | |||
| 0% | |||
| 80% | |||
| 80% | |||
| 90% | |||
|- | |||
|Squamous cell carcinoma, keratainizing (KSCC) | |||
| 30% | |||
| 90% | |||
| 60% | |||
| 90% | |||
| 80% | |||
| 90% | |||
|- | |||
|} | |||
==See also== | ==See also== | ||