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Difference between revisions of "Rhabdomyosarcoma"
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→Alveolar rhabdomyosarcoma
(→IHC: fix sp.) |
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==Molecular diagnostics== | ==Molecular diagnostics== | ||
===Alveolar rhabdomyosarcoma=== | ===Alveolar rhabdomyosarcoma=== | ||
Common translocations (~ | Common translocations (~85% of cases): | ||
*t(1,13). | *t(1,13). | ||
**PAX7/FKHR fusion gene. | **PAX7/FKHR fusion gene. | ||
*t(2,13).<ref>URL: [http://www.ncbi.nlm.nih.gov/omim/606597 http://www.ncbi.nlm.nih.gov/omim/606597]. Accessed on: 18 August 2010.</ref> | **Seen in approx. 15% of cases. | ||
*t(2,13) ~ 70% of cases.<ref>URL: [http://www.ncbi.nlm.nih.gov/omim/606597 http://www.ncbi.nlm.nih.gov/omim/606597]. Accessed on: 18 August 2010.</ref> | |||
**PAX3/FKHR fusion gene. | **PAX3/FKHR fusion gene. | ||
**Seen in approx. 70% of cases. | |||
Notes: | Notes: | ||