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→Malformation of cortical development(MCD): + Lissencephaly
Jensflorian (talk | contribs) (→CNS malformations: molecular) |
Jensflorian (talk | contribs) (→Malformation of cortical development(MCD): + Lissencephaly) |
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==Malformation of cortical development(MCD) == | ==Malformation of cortical development(MCD) == | ||
===Lissencephaly=== | |||
* Greek: ‘lissos': smooth and ‘enkephalos': brain. | |||
* Absent (agyria) or decreased (pachygyria) convolutions. | |||
* Cortical thickening | |||
* Smooth cerebral surface | |||
* Subtypes with different layering: 2-layered, 3-layered, and 4-layered forms. | |||
* Heterotopic neurons in a pattern suggestive of laminar organization. | |||
===Polymicrogyria=== | ===Polymicrogyria=== | ||
* Abnormal cortical lamination. | * Abnormal cortical lamination. | ||