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Difference between revisions of "Pineal gland"
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→Pineal parenchymal tumor of intermediate differentiation: +Molecular
Jensflorian (talk | contribs) (Pineoblastoma →Molecular) |
Jensflorian (talk | contribs) |
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*Usually no pinecytomatous rosettes. | *Usually no pinecytomatous rosettes. | ||
*High pleomorphism possible. | *High pleomorphism possible. | ||
===Molecular=== | |||
* Insertions in KBTBD4.<ref name="pmid31768671">{{cite journal |vauthors=Pfaff E, Aichmüller C, Sill M, Stichel D, Snuderl M, Karajannis MA, Schuhmann MU, Schittenhelm J, Hasselblatt M, Thomas C, Korshunov A, Rhizova M, Wittmann A, Kaufhold A, Iskar M, Ketteler P, Lohmann D, Orr BA, Ellison DW, von Hoff K, Mynarek M, Rutkowski S, Sahm F, von Deimling A, Lichter P, Kool M, Zapatka M, Pfister SM, Jones DTW |title=Molecular subgrouping of primary pineal parenchymal tumors reveals distinct subtypes correlated with clinical parameters and genetic alterations |journal=Acta Neuropathol |volume=139 |issue=2 |pages=243–257 |date=February 2020 |pmid=31768671 |doi=10.1007/s00401-019-02101-0 |url=}}</ref> | |||
* PTEN alterations. | |||
Images: | Images: | ||