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Difference between revisions of "Microcystic elongated and fragmented glands in endometrioid endometrial carcinoma"
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Microcystic elongated and fragmented glands in endometrioid endometrial carcinoma (view source)
Revision as of 15:48, 5 March 2020
, 15:48, 5 March 2020→Microscopic
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==Microscopic== | ==Microscopic== | ||
Features: | Features: | ||
* | *Irregular elongated glands ("microcystic elongated fragmented") - at deep aspect of tumour. | ||
** | **Surrounded by stromal mucin.<ref name=pmid19900084>{{cite journal |authors=Stewart CJ, Brennan BA, Leung YC, Little L |title=MELF pattern invasion in endometrial carcinoma: association with low grade, myoinvasive endometrioid tumours, focal mucinous differentiation and vascular invasion |journal=Pathology |volume=41 |issue=5 |pages=454–9 |date=2009 |pmid=19900084 |doi=10.1080/00313020903041135 |url=}}</ref> | ||
*Lymphovascular invasion more commmon than non-MELF carcinomas.<ref name=pmid24487466>{{cite journal |vauthor=Hertel JD, Huettner PC, Pfeifer JD |title=Lymphovascular space invasion in microcystic elongated and fragmented (MELF)-pattern well-differentiated endometrioid adenocarcinoma is associated with a higher rate of lymph node metastasis |journal=Int. J. Gynecol. Pathol. |volume=33 |issue=2 |pages=127–34 |date=March 2014 |pmid=24487466 |doi=10.1097/PGP.0b013e318285657b |url=}}</ref> | **May be confused with LVI. | ||
*Lymphovascular invasion more commmon than non-MELF carcinomas.<ref name=pmid24487466>{{cite journal |vauthor=Hertel JD, Huettner PC, Pfeifer JD |title=Lymphovascular space invasion in microcystic elongated and fragmented (MELF)-pattern well-differentiated endometrioid adenocarcinoma is associated with a higher rate of lymph node metastasis |journal=Int. J. Gynecol. Pathol. |volume=33 |issue=2 |pages=127–34 |date=March 2014 |pmid=24487466 |doi=10.1097/PGP.0b013e318285657b |url=}}</ref> | |||
Note: | |||
*Mucinous differentiation common in MELF. | |||
==See also== | ==See also== | ||