Account-creators
1,040
edits
Difference between revisions of "Angiocentric glioma"
Jump to navigation
Jump to search
→Molecular: Morphological spectrum
Jensflorian (talk | contribs) (→Microscopic: DDx) |
Jensflorian (talk | contribs) (→Molecular: Morphological spectrum) |
||
| Line 66: | Line 66: | ||
* Deletion-truncation breakpoints in MYB/MYBL on 6q23-<ref>{{Cite journal | last1 = Ramkissoon | first1 = LA. | last2 = Horowitz | first2 = PM. | last3 = Craig | first3 = JM. | last4 = Ramkissoon | first4 = SH. | last5 = Rich | first5 = BE. | last6 = Schumacher | first6 = SE. | last7 = McKenna | first7 = A. | last8 = Lawrence | first8 = MS. | last9 = Bergthold | first9 = G. | title = Genomic analysis of diffuse pediatric low-grade gliomas identifies recurrent oncogenic truncating rearrangements in the transcription factor MYBL1. | journal = Proc Natl Acad Sci U S A | volume = 110 | issue = 20 | pages = 8188-93 | month = May | year = 2013 | doi = 10.1073/pnas.1300252110 | PMID = 23633565 }}</ref> | * Deletion-truncation breakpoints in MYB/MYBL on 6q23-<ref>{{Cite journal | last1 = Ramkissoon | first1 = LA. | last2 = Horowitz | first2 = PM. | last3 = Craig | first3 = JM. | last4 = Ramkissoon | first4 = SH. | last5 = Rich | first5 = BE. | last6 = Schumacher | first6 = SE. | last7 = McKenna | first7 = A. | last8 = Lawrence | first8 = MS. | last9 = Bergthold | first9 = G. | title = Genomic analysis of diffuse pediatric low-grade gliomas identifies recurrent oncogenic truncating rearrangements in the transcription factor MYBL1. | journal = Proc Natl Acad Sci U S A | volume = 110 | issue = 20 | pages = 8188-93 | month = May | year = 2013 | doi = 10.1073/pnas.1300252110 | PMID = 23633565 }}</ref> | ||
* MYB-QKI rearrangements <ref>{{Cite journal | last1 = Bandopadhayay | first1 = P. | last2 = Ramkissoon | first2 = LA. | last3 = Jain | first3 = P. | last4 = Bergthold | first4 = G. | last5 = Wala | first5 = J. | last6 = Zeid | first6 = R. | last7 = Schumacher | first7 = SE. | last8 = Urbanski | first8 = L. | last9 = O'Rourke | first9 = R. | title = MYB-QKI rearrangements in angiocentric glioma drive tumorigenicity through a tripartite mechanism. | journal = Nat Genet | volume = 48 | issue = 3 | pages = 273-82 | month = Mar | year = 2016 | doi = 10.1038/ng.3500 | PMID = 26829751 }}</ref> | * MYB-QKI rearrangements <ref>{{Cite journal | last1 = Bandopadhayay | first1 = P. | last2 = Ramkissoon | first2 = LA. | last3 = Jain | first3 = P. | last4 = Bergthold | first4 = G. | last5 = Wala | first5 = J. | last6 = Zeid | first6 = R. | last7 = Schumacher | first7 = SE. | last8 = Urbanski | first8 = L. | last9 = O'Rourke | first9 = R. | title = MYB-QKI rearrangements in angiocentric glioma drive tumorigenicity through a tripartite mechanism. | journal = Nat Genet | volume = 48 | issue = 3 | pages = 273-82 | month = Mar | year = 2016 | doi = 10.1038/ng.3500 | PMID = 26829751 }}</ref> | ||
Note: Gliomas with MYB/MYBL alteration may histologically resemble diffuse astrocytoma in children but these tumors cluster together with angiocentric glioma suggesting a single tumor entity.<ref>{{Cite journal | last1 = Chiang | first1 = J. | last2 = Harreld | first2 = JH. | last3 = Tinkle | first3 = CL. | last4 = Moreira | first4 = DC. | last5 = Li | first5 = X. | last6 = Acharya | first6 = S. | last7 = Qaddoumi | first7 = I. | last8 = Ellison | first8 = DW. | title = A single-center study of the clinicopathologic correlates of gliomas with a MYB or MYBL1 alteration. | journal = Acta Neuropathol | volume = 138 | issue = 6 | pages = 1091-1092 | month = Dec | year = 2019 | doi = 10.1007/s00401-019-02081-1 | PMID = 31595312 }}</ref> | |||